Clarinex (Desloratadine) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Clarinex

Eye Allergy »

Eye allergy facts

Most allergic eye conditions are more irritating than dangerous.
Allergic or vernal keratoconjunctivitis may result in scarring of the cornea and visual problems.
Itchy eyes are probably allergic eyes.
Topical antihistamine/decongestant preparations are effective and safe for mildly itchy, red eyes.
Patanol, a topical mast-cell stabilizer, is a safe, highly effective, long-acting treatment.
Topical steroids should be used with caution and under the supervision of an ophthalmologist.
If in doubt, seek medical advice sooner rather than later.

Eye allergy introduction

The eyes are the windows to the soul because they reflect our state of mind. This certainly can't be true if our eyes are red, swollen, watery, and itchy from an allergic reaction. Severe allergic eye symptoms can be very distressing and are a common reason fo...

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CLARINEX®
(desloratadine) Tablets, Syrup, Reditabs® Tablets

DRUG DESCRIPTION

CLARINEX (desloratadine) Tablets are light blue, round, film coated tablets containing 5 mg desloratadine, an antihistamine, to be administered orally. It also contains the following excipients: dibasic calcium phosphate dihydrate USP, microcrystalline cellulose NF, corn starch N F, talc USP, carnauba wax N F, white wax NF, coating material consisting of lactose monohydrate, hypromellose, titanium dioxide, polyethylene glycol, and FD&C Blue #2 Aluminum Lake.

CLARINEX (desloratadine) Syrup is a clear orange colored liquid containing 0.5 mg/1 mL desloratadine. The syrup contains the following inactive ingredients: propylene glycol USP, sorbitol solution USP, citric acid (anhydrous) USP, sodium citrate dihydrate USP, sodium benzoate N F, disodium edetate USP, purified water USP. It also contains granulated sugar, natural and artificial flavor for bubble gum and FDC Yellow #6 dye.

The CLARINEX RediTabs® brand of desloratadine orally-disintegrating tablets are light red, flat-faced, round, speckled tablets with an “A” debossed on one side for the 5 mg tablets and a “K” debossed on one side for the 2.5 mg tablets. Each RediTabs Tablet contains either 5 mg or 2.5 mg of desloratadine. It also contains the following inactive ingredients: mannitol USP, microcrystalline cellulose N F, pregelatinized starch, N F, sodium starch glycolate, N F, magnesium stearate N F, butylated methacrylate copolymer, crospovidone, NF, aspartame N F, citric acid USP, sodium bicarbonate USP, colloidal silicon dioxide, N F, ferric oxide red NF and tutti frutti flavoring.

Desloratadine is a white to off-white powder that is slightly soluble in water, but very soluble in ethanol and propylene glycol. It has an empirical formula: C₁₉H₁₉ClN₂ and a molecular weight of 310.8. The chemical name is 8-chloro-6,11-dihydro-11-(4-piperdinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine and has the following structure:

CLARINEX®
(desloratadine) Structural Formula Illustration

What are the possible side effects of desloratadine (Clarinex, Clarinex Reditabs)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

fast, pounding, or uneven heartbeat;
fever, flu symptoms;
seizure (convulsions); or
jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

dry mouth, sore throat, cough;

Read All Potential Side Effects and See Pictures of Clarinex »

What are the precautions when taking desloratadine (Clarinex)?

Before taking desloratadine, tell your doctor or pharmacist if you are allergic to it; or to loratadine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease.

Limit alcohol intake, as it may intensify drug side effects.

Desloratadine should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before...

Read All Potential Precautions of Clarinex »

Last reviewed on RxList: 7/10/2009
This monograph has been modified to include the generic and brand name in many instances.