October 4, 2015
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Clemastine Fumarate Syrup

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Clemastine Fumarate Syrup

Side Effects


The most frequent adverse reactions are italicized:

Nervous System

Sedation, sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesia, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, hysteria, neuritis, convulsions.

Gastrointestinal System

Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation.

Respiratory System

Thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness.

Cardiovascular System

Hypotension, headache, palpitations, tachycardia, extrasystoles.

Hematologic System

Hemolytic anemia, thrombocytopenia, agranulocytosis.

Genitourinary System

Urinary frequency, difficult urination, urinary retention, early menses.


Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of mouth, nose and throat.

Read the Clemastine Fumarate Syrup (clemastine fumarate syrup) Side Effects Center for a complete guide to possible side effects


Additive CNS depression may occur when antihistamines are administered concomitantly with other CNS depressants including barbiturates, tranquilizers, and alcohol. Patients receiving antihistamines should be advised against the concurrent use of other CNS depressant drugs.

Monoamine oxidase (MAO) inhibitors prolong and intensify the anticholinergic effects of antihistamines.

Last reviewed on RxList: 8/11/2008
This monograph has been modified to include the generic and brand name in many instances.

Side Effects

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Allergies & Asthma

Improve treatments & prevent attacks.