May 24, 2016
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Cleocin T

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Cleocin T

Side Effects


In 18 clinical studies of various formulations of CLEOCIN T using placebo vehicle and/or active comparator drugs as controls, patients experienced a number of treatment emergent adverse dermatologic events [see table below].

Number of Patients Reporting Events

Treatment Emergent Adverse Event Solution
n=553 (%)
n=148 (%)
n=160 (%)
Burning  62 (11)  15 (10)  17 (11) 
Itching  36 ( 7)  15 (10)  17 (11) 
Burning/Itching  60 (11)  # ( – )  # ( – ) 
Dryness  105 (19)  34 (23)  29 (18) 
Erythema  86 (16)  10 ( 7)  22 (14) 
Oiliness/Oily Skin  8 ( 1)  26 (18)  12* (10) 
Peeling  61 (11)  # ( – )  11 ( 7) 
# not recorded
* of 126 subjects

Orally and parenterally administered clindamycin has been associated with severe colitis which may end fatally.

Cases of diarrhea, bloody diarrhea and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see WARNINGS).

Abdominal pain and gastrointestinal disturbances as well as gram-negative folliculitis have also been reported in association with the use of topical formulations of clindamycin.

Read the Cleocin T (clindamycin topical) Side Effects Center for a complete guide to possible side effects


Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore it should be used with caution in patients receiving such agents.

Read the Cleocin T Drug Interactions Center for a complete guide to possible interactions

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 4/17/2014

Side Effects

Cleocin T - User Reviews

Cleocin T User Reviews

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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