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Cleocin Vaginal Ovules

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Cleocin Vaginal Ovules

Cleocin® Vaginal Ovules
(clindamycin phosphate) Vaginal Suppositories

Cleocin Vaginal Ovules

DRUG DESCRIPTION

Clindamycin phosphate is a water-soluble ester of the semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2(dihydrogen phosphate). The monohydrate form has a molecular weight of 522.98, and the molecular formula is C18H34ClN2O8PS•H2O. The structural formula is represented below:

Cleocin® Vaginal Ovules (clindamycin phosphate vaginal suppositories) Structural Formula Illustration

CLEOCIN Vaginal Ovules are semisolid, white to off-white suppositories for intravaginal administration. Each 2.5 g suppository contains clindamycin phosphate equivalent to 100 mg clindamycin in a base consisting of a mixture of glycerides of saturated fatty acids.

What are the possible side effects of clindamycin vaginal (Cleocin Vaginal)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using clindamycin vaginal and call your doctor at once if you have diarrhea that is watery or bloody.

Keep using clindamycin vaginal and talk to your doctor if you have any of these less serious side effects:

  • mild nausea or stomach pain;
  • constipation, gas;
  • vaginal itching, discharge, or pain; or
  • changes in your menstrual periods; or
  • mild skin rash or...

Read All Potential Side Effects and See Pictures of Cleocin Vaginal Ovules »

Last reviewed on RxList: 7/11/2013
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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