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Cleviprex

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Cleviprex

OVERDOSE

There has been no experience of overdosage in human clinical trials. In clinical trials, doses of Cleviprex up to 106 mg/hour or 1153 mg maximum total dose were administered. The expected major effects of overdose would be hypotension and reflex tachycardia.

Discontinuation of Cleviprex leads to a reduction in antihypertensive effects within 5 to 15 minutes [see CLINICAL PHARMACOLOGY]. In case of suspected overdosage, Cleviprex should be discontinued immediately and the patient's blood pressure should be supported.

CONTRAINDICATIONS

Known Allergy

Cleviprex is contraindicated in patients with allergies to soybeans, soy products, eggs, or egg products.

Defective Lipid Metabolism

Cleviprex is contraindicated in patients with defective lipid metabolism such as pathologic hyperlipemia, lipoid nephrosis, or acute pancreatitis if it is accompanied by hyperlipidemia.

Severe Aortic Stenosis

Cleviprex is contraindicated in patients with severeaortic stenosis because afterload reduction can be expected to reduce myocardial oxygen delivery.

Last reviewed on RxList: 1/4/2012
This monograph has been modified to include the generic and brand name in many instances.

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