"Oct. 24, 2012 -- Women who take hormones within five years of menopause may have a slightly lower risk of Alzheimer's disease compared to women who don't ever take them, a new study shows.
The study, which is published in the journal"...
Climara Pro Patient Information including How Should I Take
In this Article
- What are estradiol and levonorgestrel (Climara Pro)?
- What are the possible side effects of estradiol and levonorgestrel (Climara Pro)?
- What is the most important information I should know about estradiol and levonorgestrel (Climara Pro)?
- What should I discuss with my healthcare provider before using estradiol and levonorgestrel (Climara Pro)?
- How should I use estradiol and levonorgestrel (Climara Pro)?
- What happens if I miss a dose (Climara Pro)?
- What happens if I overdose (Climara Pro)?
- What should I avoid while using estradiol and levonorgestrel (Climara Pro)?
- What other drugs will affect estradiol and levonorgestrel (Climara Pro)?
- Where can I get more information?
What should I discuss with my healthcare provider before using estradiol and levonorgestrel (Climara Pro)?
You should not use estradiol and levonorgestrel if you have had a hysterectomy, or if you have any of the following:
- a history of stroke, heart attack, or blood clots;
- liver disease;
- unusual vaginal bleeding; or
- a history of breast, uterine, or hormone-related cancer.
Before using estradiol and levonorgestrel, tell your doctor if you have:
- high blood pressure, angina, or heart disease;
- kidney disease;
- a history of gallbladder disease;
- a thyroid disorder; or
If you have any of the conditions listed above, you may not be able to use estradiol and levonorgestrel, or you may need a dosage adjustment or special tests during treatment.
You may need to stop using estradiol and levonorgestrel for a short time if you will have surgery or you become ill and must stay in bed for any length of time. Tell any doctor who treats you that you are using this medication.
This medication should not be used to prevent heart disease or dementia. Using estrogens long-term may actually increase your risk of heart attack, stroke, dementia, breast cancer, or blood clots. This risk is higher if you are overweight, if you smoke tobacco or have diabetes, high blood pressure, systemic lupus erythematosus, high cholesterol or high triglycerides. Talk with your doctor about your individual risks and benefits if you plan to use estradiol and levonorgestrel long-term.
Estradiol may increase your risk of developing endometrial hyperplasia, a condition that can lead to cancer of the uterus. Using levonorgestrel (a progestin) with estradiol can lower the risk of developing this condition.
Have yearly physical exams and examine your breasts for lumps on a monthly basis while using estradiol and levonorgestrel. It is important that you not miss any scheduled visits to your doctor. Call your doctor at any time if you have unusual vaginal bleeding.
FDA pregnancy category X: This medication can cause birth defects. Do not use estradiol and levonorgestrel if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
Estradiol and levonorgestrel may cause problems with breast-feeding and can affect breast milk. Do not use estradiol and levonorgestrel without telling your doctor if you are breast-feeding a baby.
How should I use estradiol and levonorgestrel (Climara Pro)?
Use the estradiol and levonorgestrel patches exactly as your doctor has prescribed them for you. Do not use more patches than recommended or use them for longer than your doctor has prescribed.
If you have been using another form of estrogen and progestin and are switching to estradiol and levonorgestrel skin patches, finish your current cycle of treatment first. If you are not already using an estrogen or progestin, you may begin using the skin patches at any time.
To use estradiol and levonorgestrel patches:
- Apply each patch to a clean, dry, and smooth (fold free) area of skin on the lower stomach (below the belly button). Do not use the patch on your breasts or at your waistline, where tight-fitting clothing may interfere with its use. Do not apply to broken or irritated skin.
- Open the pouch and take out the patch. Remove one side of the protective liner, trying not to touch the sticky part. Apply the patch and then remove the second side of the liner. Press the patch firmly in place with your hand for at least 10 seconds, making sure there is good contact, especially around the edges.
- If a patch falls off, reapply it to another place on your lower abdomen. If it will not stick, apply a new patch.
- The patch should be worn around-the-clock for one week. Replace the patch on the same day each week as directed by your doctor. Use only one patch at a time.
- Choose a new place on your lower abdomen each time you apply a patch. Allow at least 1 week to pass before applying a patch to the same place.
- Do not cut the patches.
- After one week, remove the patch and fold it in half so that it sticks to itself. Used patches still contain active hormones and should be discarded out of the reach of children and pets.
- Remove the patch carefully and slowly to avoid irritating your skin. Any adhesive remaining on the skin can be removed with baby oil.
To be sure this medication is helping your condition, you will need to have regular physical exams every 3 to 6 months. You may also need breast mammograms. It is important that you not miss any scheduled visits to your doctor. Call your doctor at any time if you have unusual vaginal bleeding.
If you use this medication to prevent osteoporosis, your doctor may also recommend weight-bearing exercise, calcium and vitamin D supplements, and dietary changes. Follow these directions carefully and ask your doctor before using any supplements.
Store the patches in their sealed foil pouches at room temperature away from moisture, heat, and direct light.
Additional Climara Pro Information
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