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Clindets Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 3/18/2016

Clindets (clindamycin) is a topical solution of an antibiotic used for treating acne. Side effects of Clindets include:

  • skin burning
  • itching
  • dryness
  • redness
  • oiliness, and
  • peeling

A thin film dose of Clindets should be applied to affected areas twice daily with an applicator. Clindets may interact with other neuromuscular blocking agents. Tell your doctor all medications and supplements you use. During pregnancy, Clindets should only be used if prescribed. It is unknown if Clindets passes into breast milk. Oral and intravenous forms of clindamycin pass into breast milk. Consult your doctor before breastfeeding.

Our Clindets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Clindets FDA Prescribing Information: Side Effects
(Adverse Reactions)


In 18 clinical studies of various topical formulations of clindamycin phosphate using placebo vehicle and/or active comparator drugs as controls, patients experienced a number of treatment emergent adverse dermatological events (see table below).


Number of patients reporting events
Treatment Emergent
Adverse Event
n=553 (%)
n=148 (%)
n=160 (%)
62 (11)
15 (10)
17 (11)
36 (7)
15 (10)
17 (11)
60 (11)
# (-)
# (-)
105 (19)
34 (23)
29 (18)
86 (16)
10 (7)
22 (14)
Oiliness/Oily Skin
8 (1)
26 (18)
12 * (10)
61 (11)
# (-)
11 (7)
# not recorded     
* of 126 subjects

Read the entire FDA prescribing information for Clindets (Clindamycin)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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