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Clindets Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Clindets (clindamycin) is a topical solution of an antibiotic used for treating acne. Side effects of Clindets include:
- skin burning
- oiliness, and
A thin film dose of Clindets should be applied to affected areas twice daily with an applicator. Clindets may interact with other neuromuscular blocking agents. Tell your doctor all medications and supplements you use. During pregnancy, Clindets should only be used if prescribed. It is unknown if Clindets passes into breast milk. Oral and intravenous forms of clindamycin pass into breast milk. Consult your doctor before breastfeeding.
Our Clindets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Clindets FDA Prescribing Information: Side Effects
Clinical Trial Adverse Drug Reactions
The safety was assessed in 150 acne vulgaris patients from a placebo-controlled study in which CLINDETS® or placebo (vehicle) pledgets were applied twice daily over a period of 11 weeks. The number of patients with worsening scores of erythema, peeling and burning is presented in Table 1.
Table 1: Patients with worsening signs or symptoms of acne in a CLINDETS®
|Signs and Symptoms||Treatment||Number of Patients with Worsening Score|
administrative site conditions
|Erythema||CLINDETS®||1/73 (1.4)||2/72 (2.8)||0||0|
|Vehicle||1/72 (1.4)||2/70 (2.9)||0||0|
|Peeling||CLINDETS®||2/73 (2.7)||2/72 (2.8)||1/73 (1.4)||0|
|Vehicle||1/72 (1.4)||3/70 (4.3)||0||0|
|Burning||CLINDETS®||4/73 (5.5)||1/72 (1.4)||2/73 (2.7)||1/73 (1.4)|
|Vehicle||4/72 (5.6)||4/70 (5.7)||0||0|
|* Change from Baseline of Signs and Symptoms||
Number of patients reporting common (≥1%) treatment emergent adverse reactions are provided in Table 2.
Table 2: Most common drug related adverse reactions reported by ≥1% of
patients in a CLINDETS® Clinical Trial
|Adverse Drug Reaction||CLINDETS®
Additional Adverse Drug Reactions Reported In Other Clindamycin Phosphate Clinical Trials
The following additional common adverse drug reactions (≥ 1%) have been reported in clinical trials involving other clindamycin phosphate formulations:
Immune system disorders: urticaria, whealing, swollen lips.
Gastrointestinal disorders: abdominal cramping.
Post-Market Adverse Drug Reactions
Immune system disorders: allergic reaction.
Read the entire FDA prescribing information for Clindets (Clindamycin)
Additional Clindets Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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