May 26, 2017
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Clinoril Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking sulindac (Clinoril)?

Do not use sulindac just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking sulindac, especially in older adults.

Do not use this medication if you are allergic to sulindac, or to aspirin or other NSAIDs.

To make sure you can safely take sulindac, tell your doctor if you have any of these other conditions:

  • a history of heart attack, stroke, or blood clot;
  • heart disease, congestive heart failure, high blood pressure;
  • a history of stomach ulcers or bleeding, bowel problems, diverticulosis;
  • liver or kidney disease;
  • asthma;
  • polyps in your nose; or
  • if you smoke.

FDA pregnancy category C. It is not known whether sulindac will harm an unborn baby. Taking sulindac during the last 3 months of pregnancy may result in birth defects. Do not take sulindac during pregnancy unless your doctor has told you to.

It is not known whether sulindac passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to a child without the advice of a doctor.

How should I take sulindac (Clinoril)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

The maximum amount of sulindac for adults is 400 milligrams (mg) per day. Know the amount of sulindac in the specific product you are taking.

If you take sulindac for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Visit your doctor regularly.

Store at room temperature, away from moisture, heat, and light.

Side Effects Centers

Clinoril - User Reviews

Clinoril User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Clinoril sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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