May 27, 2017
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How Supplied


Clobevate (clobetasol propionate gel) is a super-high potency corticosteroid formulation indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in children under 12 years of age is not recommended.


Apply a thin layer of Clobevate (clobetasol propionate gel) to the affected areas twice daily and rub in gently and completely (see INDICATIONS AND USAGE).

Clobevate (clobetasol propionate gel) is a super-high potency topical corticosteroid; therefore, treatment should be limited to 2 consecutive weeks, and amounts greater than 50 g per week should not be used.

As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary.

Clobevate (clobetasol propionate gel) should not be used with occlusive dressings.


Clobevate® (Clobetasol Propionate Gel) 0.05% is supplied in 45-g (NDC 0145-2790-04) tubes.

Store between 15° and 30°C (59° and 86°F). Clobevate (clobetasol propionate gel) should not be refrigerated.

Stiefel Laboratories, Inc. Coral Gables, FL 33134. Rev. 0804

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 4/18/2017

How Supplied

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