home > drugs a-z list > clobex spray (clobetasol propionate spray) drug center > clobex spray (clobetasol propionate spray) drug

Recommended Topic Related To:

Clobex

Psoriasis facts

  • Psoriasis is a chronic inflammatory skin disease.
  • Psoriasis has no known cause.
  • The tendency toward developing psoriasis is inherited in genes.
  • Psoriasis is not contagious.
  • Psoriasis gets better and worse spontaneously and can have periodic remissions (clear skin).
  • Psoriasis is controllable with medication.
  • Psoriasis is currently not curable.
  • There are many promising therapies, including newer biologic drugs.
  • Future research for psoriasis is promising.

What is psoriasis?

Psoriasis is a noncontagious skin condition that produces red, dry plaques of thickened skin. The dry flakes and skin scales are thought to result from the rapid proliferation of skin cells that is triggered by abnormal lymphocytes from the blood . Psoriasis commonly affects the skin of the elbows, knees, and scalp.

Some people have such mild ps...

Clobex Spray

font size

CLOBEX®
(clobetasol propionate) Spray, 0.05%

DRUG DESCRIPTION

CLOBEX® Spray, 0.05% contains clobetasol propionate, a synthetic fluorinated corticosteroid, for topical use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents. Clobetasol propionate is 21-chloro-9-fluoro-11β, 17-dihydroxy-16β -methylpregna-1,4-diene-3,20-dione 17-propionate, with the empirical formula C25H32CIFO5, and a molecular weight of 466.97 (CAS Registry Number 25122-46-7).

The following is the chemical structure:

CLOBEX® (clobetasol propionate)  Structural Formula Illustration

Clobetasol propionate is a white to almost white crystalline powder that is practically insoluble in water. Each gram of CLOBEX® Spray, 0.05% contains 0.5 mg of clobetasol propionate, in a vehicle base composed of alcohol, isopropyl myristate, sodium lauryl sulfate, and undecylenic acid.

What are the possible side effects of clobetasol topical?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clobetasol topical through your skin, such as:

  • blurred vision, or seeing halos around lights;
  • mood changes;
  • sleep problems (insomnia);
  • weight gain, puffiness in your face; or
  • muscle...

Read All Potential Side Effects and See Pictures of Clobex Spray »

What are the precautions when taking clobetasol propionate spray (Clobex Spray)?

Before using clobetasol, tell your doctor or pharmacist if you are allergic to it; or to any other steroids (e.g., hydrocortisone, dexamethasone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, other skin conditions (e.g., rosacea, perioral dermatitis), immune system problems.

Do not use if there is an infection or sore in the area to be treated.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress....

Read All Potential Precautions of Clobex Spray »

Last reviewed on RxList: 2/25/2011
This monograph has been modified to include the generic and brand name in many instances.

Clobex Spray - User Reviews

Clobex Spray User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Clobex Spray sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.