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Clobex Lotion

Psoriasis facts

  • Psoriasis is a chronic inflammatory skin disease.
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What is psoriasis?

Psoriasis is a noncontagious skin condition that produces red, dry plaques of thickened skin. The dry flakes and skin scales are thought to result from the rapid proliferation of skin cells that is triggered by abnormal lymphocytes from the blood . Psoriasis commonly affects the skin of the elbows, knees, and scalp.

Some people have such mild ps...

Clobex Lotion

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Clobex® Lotion
(clobetasol propionate) Lotion, 0.05%

For dermatologic use only

Not for ophthalmic, oral or intravaginal use

DRUG DESCRIPTION

CLOBEX® (clobetasol propionate) Lotion, 0.05% contains clobetasol propionate, a synthetic fluorinated corticosteroid, for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents. Clobetasol propionate is 21-chloro-9-fluoro-11β,17-dihydroxy-16β -methylpregna-1,4-diene-3, 20-dione17-propionate, with the empirical formula C25H32CIFO5, a molecular weight of 466.98 (CAS Registry Number 25122-46-7).O

The following is the chemical structure:

CLOBEX® (clobetasol propionate)  structural formula illustration

Clobetasol propionate is a white to practically-white crystalline powder insoluble in water.

Each gram of CLOBEX® (clobetasol propionate) Lotion, 0.05% contains 0.5 mg of clobetasol propionate, in a vehicle base composed of hypromellose, propylene glycol, mineral oil, polyoxyethylene glycol 300 isostearate, carbomer 1342, sodium hydroxide and purified water.

What are the possible side effects of clobetasol topical?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clobetasol topical through your skin, such as:

  • blurred vision, or seeing halos around lights;
  • mood changes;
  • sleep problems (insomnia);
  • weight gain, puffiness in your face; or
  • muscle...

Read All Potential Side Effects and See Pictures of Clobex Lotion »

Last reviewed on RxList: 12/1/2008
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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