May 26, 2017
Recommended Topic Related To:

Clobex Lotion

" The risk for immunoglobulin A nephropathy is five times higher in people with severe psoriasis than in those without. And the risk for overall glomerular disease is two times higher.

These findings come from an analysis of data "...


Clobex Lotion

Side Effects


In controlled clinical trials with CLOBEX® (clobetasol propionate) Lotion, 0.05%, the following adverse reactions have been reported: burning/stinging, skin dryness, irritation, erythema, folliculitis, pruritus, skin atrophy, and telangiectasia.

The pooled incidence of local adverse reactions in trials for psoriasis and atopic dermatitis with CLOBEX® (clobetasol propionate) Lotion, 0.05% at 1.0% or greater was:

Adverse Reaction Incidence
Skin Atrophy 4.20%
Telangiectasia 3.20%
Discomfort Skin 1.30%
Skin Dry 1.00%

Other local adverse events occurred at rates less than 1.0%. Similar rates of local adverse reactions were reported in the comparator (clobetasol propionate cream, 0.05%). Most local adverse events were rated as mild to moderate and they are not affected by age, race or gender.

The following additional local adverse reactions have been reported with topical corticosteroids. They may occur more frequently with the use of occlusive dressings and higher potency corticosteroids, including clobetasol propionate. These reactions are listed in an approximate decreasing order of occurrence: irritation, dryness, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, striae and miliaria.

Read the Clobex Lotion (clobetasol propionate lotion) Side Effects Center for a complete guide to possible side effects


No information provided.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 8/30/2012

Side Effects

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