Clobex Shampoo

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Clobex® Shampoo
(clobetasol propionate) Shampoo, 0.05%

For External Use Only. Not for Ophthalmic Use.

DRUG DESCRIPTION

CLOBEX® (clobetasol propionate) Shampoo, 0.05%, contains clobetasol propionate, a synthetic fluorinated corticosteroid, for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.

The chemical name of clobetasol propionate is 21-chloro-9-fluoro-11β,17-dihydroxy-16β -methylpregna-1, 4-diene-3, 20-dione 17-propionate.

It has the following structural formula:

CLOBEX® (clobetasol propionate)  structural formula illustration

Clobetasol propionate has a molecular weight of 466.97 (CAS Registry Number 25122-46-7). The molecular formula is C25H32CIFO5. Clobetasol propionate is a white to practically white crystalline, odorless powder insoluble in water.

Each mL of CLOBEX® (clobetasol propionate) Shampoo,0.05%, contains clobetasol propionate, 0.05%, in a shampoo base consisting of alcohol, citric acid, coco-betaine, polyquaternium-10, purified water, sodium citrate, and sodium laureth sulfate.

Last reviewed on RxList: 12/1/2008
This monograph has been modified to include the generic and brand name in many instances.

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