Clobex Shampoo
SIDE EFFECTS
In clinical trials with CLOBEX® Shampoo (clobetasol propionate shampoo) , the following adverse reactions have been reported: burning/stinging, pruritus, edema, folliculitis, acne, dry skin, irritant dermatitis, alopecia, urticaria, skin atrophy and telangiectasia.
The table below summarizes selected adverse events that occurred in at least 1% of subjects in the Phase 2 and 3 studies for scalp psoriasis.
Summary of Selected Adverse Events ≥ 1% by
Body System
| Body System | Clobetasol Propionate Shampoo N=558 |
Vehicle Shampoo N=127 |
| Skin and Appendages | 49 (8.8%) | 28 (22.0%) |
| Discomfort Skin | 26 (4.7%) | 16 (12.6%) |
| Pruritus | 3 (0.5%) | 9 (7.1%) |
| Body As A Whole | 33 (5.9%) | 12 (9.4%) |
| Headache | 10 (1.8%) | 1 (0.8%) |
The following additional local adverse reactions have been reported infrequently with other topical corticosteroids, and they may occur more frequently with the use of occlusive dressings, especially with higher potency corticosteroids. These reactions are listed in an approximately decreasing order of occurrence: hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, and miliaria.
Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.
Read the Clobex Shampoo (clobetasol propionate shampoo) Side Effects Center for a complete guide to possible side effects »
DRUG INTERACTIONS
No information provided.
Last reviewed on RxList: 12/1/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Clobex Shampoo Information
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