Clozaril (Clozapine) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 26, 2012

Clozaril

Schizophrenia »

Schizophrenia facts

Schizophrenia is a chronic, severe, debilitating mental illness that affects about 1% of the population, more than 2 million people in the United States alone.
With the sudden onset of severe psychotic symptoms, the individual is said to be experiencing acute schizophrenia. Psychotic means out of touch with reality or unable to separate real from unreal experiences.
There is no known single cause of schizophrenia. As discussed later, it appears that genetic factors produce a vulnerability to schizophrenia, with environmental factors contributing to different degrees in different individuals.
There are a number of various treatments for schizophrenia. Given the complexity of schizophrenia, the major questions about this disorder (its cause or causes, prevention, and treatment) are unlikely to be resolved in the near future. The public should beware of those offering "t...

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Clozaril Drug Center

Medical Editor: Melissa Conrad Stöppler, MD

Prescribing Information

For Patients

Clozaril (clozapine) is an antipsychotic medication that is used to treat severe schizophrenia symptoms in people who have not responded to other medications. Clozapine is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders. Side effects can include constipation, drooling, sleep disorders, increased sweating, or weight gain. Other side effects can occur. Clozaril is taken orally in tablet form, and an orally-disintegrating tablet that can be taken without water is available.

While you are taking clozapine, your blood may need to be tested every week for the first 6 months of treatment. It has been associated with agranulocytosis in some patients, a potentially fatal decrease in a certain type of white blood cells. Clozaril is not expected to be harmful to an unborn baby. Do not use clozapine without telling your doctor if you are pregnant or plan to become pregnant during treatment. Clozapine can pass into breast milk and may harm a nursing baby.

Our Clozaril Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and condition.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Clozaril Prescribing Information: Indications & Dosage

CLOZARIL® (clozapine) Structural Formula Illustration

Treatment-Resistant Schizophrenia

CLOZARIL® (clozapine) is indicated for the management of severely ill schizophrenic patients who fail to respond adequately to standard drug treatment for schizophrenia. Because of the significant risk of agranulocytosis and seizure associated with its use, CLOZARIL should be used only in patients who have failed to respond adequately to treatment with appropriate courses of standard drug treatments for schizophrenia, either because of insufficient effectiveness or the inability to achieve an effective dose due to intolerable...

Read the complete drug monograph for Clozaril »

What is Clozaril Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Clozaril Patient Information: Side Effects

Stop using clozapine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

feeling short of breath, even at night or with mild exertion;
swelling in your hands or feet;
fever, weakness, sore throat, stiff muscles, confusion, sweating, fast or uneven heartbeats;
sudden numbness or weakness, especially on one side of the body;
sudden headache...

Read the complete patient information for Clozaril »