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There is no information on overdoses of Coartem Tablets higher than the doses recommended for treatment.

In cases of suspected overdosage, symptomatic and supportive therapy, which would include ECG and blood electrolyte monitoring, should be given as appropriate.



  • Known hypersensitivity to artemether, lumefantrine, or to any of the excipients of Coartem Tablets [see ADVERSE REACTIONS].

Strong CYP3A4 Inducers

  • Co-administration of strong inducers of CYP3A4 such as rifampin, carbamazepine, phenytoin and St. John's wort with Coartem Tablets can result in decreased concentrations of artemether and/or lumefantrine and loss of antimalarial efficacy [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY].

Last reviewed on RxList: 5/28/2013
This monograph has been modified to include the generic and brand name in many instances.


Coartem - User Reviews

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