Coartem (Artemether Lumefantrine Tablets) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 26, 2012

Coartem

Travel Medicine »

Why should travelers see a physician before they leave on a trip?

Travelers should see a physician before leaving for a trip if

they are going to developing countries,
they are visiting sites that are not on the usual tourist routes or traveling to high altitudes,
they have chronic diseases that could be affected by travel,
they are visiting countries that require vaccinations before they allow travelers to enter the country.

The goal of a pre-travel medical evaluation is to help travelers protect themselves against (1) common diseases that may be mild but that will disrupt their trip, and (2) less common diseases that may be serious or even fatal. All travelers need to be up to date on routine vaccines they would normally get if they were not traveling. For example, an annual influenza vaccination (flu shot) is recommended if traveling during influenza season. Travelers should also be up to date on te...

Read the Travel Medicine article »

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Coartem

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Coartem Patient Information including If I Miss a Dose

What happens if I miss a dose (Coartem)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Coartem)?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an artemether and lumefantrine overdose are not known.

What should I avoid while taking artemether and lumefantrine (Coartem)?

Do not take halofantrine (Halfan) while you are taking artemether and lumefantrine or just after you stop taking it. Serious, life-threatening side effects on your heart can occur if you take these medications within 30 days of each other.

Avoid taking other anti-malaria medications while you are taking artemether and lumefantrine, unless your doctor has told you to.

Grapefruit and grapefruit juice may interact with artemether and lumefantrine and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What other drugs will affect artemether and lumefantrine (Coartem)?

Many drugs can interact with artemether and lumefantrine. Below is just a partial list. Tell your doctor if you are using:

ketoconazole (Nizoral);
cold or allergy medicines;
an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);
an antidepressant such as amitriptylline (Elavil, Vanatrip), clomipramine (Anafranil), or desipramine (Norpramin);
a heart rhythm medication such as amiodarone (Cordarone, Pacerone), disopyramide (Norpace), flecainide (Tambocor), procainamide (Procan, Pronestyl), propafenone (Rythmol), or quinidine (Quinaglute, Quinidex, Quin-Release);
HIV or AIDS medicine such as delavirdine (Rescriptor) or ritonavir (Norvir);
medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);
medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);
migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or
narcotic medication such as levomethadyl (Orlaam), or methadone (Dolophine, Methadose).

This list is not complete and there may be other drugs that can interact with artemether and lumefantrine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about artemether and lumefantrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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