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Coartem Patient Information including How Should I Take
In this Article
- What is artemether and lumefantrine (Coartem)?
- What are the possible side effects of artemether and lumefantrine (Coartem)?
- What is the most important information I should know about artemether and lumefantrine (Coartem)?
- What should I discuss with my healthcare provider before taking artemether and lumefantrine (Coartem)?
- How should I take artemether and lumefantrine (Coartem)?
- What happens if I miss a dose (Coartem)?
- What happens if I overdose (Coartem)?
- What should I avoid while taking artemether and lumefantrine (Coartem)?
- What other drugs will affect artemether and lumefantrine (Coartem)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking artemether and lumefantrine (Coartem)?
You should not use this medication if you are allergic to artemether or lumefantrine.
Many drugs can interact with artemether and lumefantrine and some should not be used at the same time. Tell your doctor about all other medications you use, especially:
- bosentan (Tracleer);
- dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
- halofantrine (Halfan) taken within the past 30 days;
- St. John's wort;
- rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
- a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);
- HIV/AIDS medication such as efavirenz (Sustiva, Atripla), etravirine (Intelence), nevirapine (Viramune), or ritonavir (Norvir, Kaletra);
- medicines to treat narcolepsy, such as armodafinil (Nuvigil) or modafinil (Progivil); or
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).
To make sure artemether and lumefantrine is safe for you, tell your doctor if you have any of these other conditions:
- a history of heart disease or a recent heart attack;
- heart rhythm disorder, or a personal or family history of Long QT syndrome;
- liver or kidney disease; or
- low levels of potassium or magnesium in your blood.
FDA pregnancy category C. It is not known whether artemether and lumefantrine is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Use a barrier form of birth control (such as a condom or diaphragm with spermicide). Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment.
It is not known whether artemether and lumefantrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Artemether and lumefantrine should not be given to a child who weighs less than 11 pounds.
How should I take artemether and lumefantrine (Coartem)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Take artemether and lumefantrine with food, milk, pudding, oatmeal, or broth. The tablet may be crushed and mixed with 1 or 2 teaspoons of water for easier swallowing. You may also mix a crushed tablet with infant formula when giving this medication to a child. Start eating normally as soon as possible to help your body better absorb the medication.
If you vomit within 1 to 2 hours after taking this medication, take another dose. If your vomiting continues or you cannot eat, call your doctor.
Artemether and lumefantrine is usually given as a total of 6 doses over a period of 3 days. Carefully follow your doctor's instructions about how many tablets to take per dose. Artemether and lumefantrine doses are based on weight and age. The usual doses are as follows, unless your doctor tells you otherwise.
For people over 16 years old who weigh at least 77 pounds:
- Take four (4) tablets as an initial dose.
- Take 4 more tablets 8 hours later.
- Take 4 tablets in the morning and 4 tablets in the evening for the next 2 days.
For children younger than 16 years old who weigh between 55 and 77 pounds:
- Take three (3) tablets as an initial dose.
- Take 3 more tablets 8 hours later.
- Take 3 tablets in the morning and 3 tablets in the evening for the next 2 days.
For children younger than 16 years old who weigh between 33 and 55 pounds:
- Take two (2) tablets as an initial dose.
- Take 2 more tablets 8 hours later.
- Take 2 tablets in the morning and 2 tablets in the evening for the next 2 days.
For children younger than 16 years old who weigh between 11 and 33 pounds:
- Take one (1) tablet as an initial dose.
- Take a second tablet 8 hours later.
- Take 1 tablet in the morning and 1 tablet in the evening for the next 2 days.
No medication is 100% effective in treating malaria. For best results, keep using the medication as directed.
Store at room temperature away from moisture and heat.
Additional Coartem Information
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