Codeine Phosphate (Codeine Phosphate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 7, 2012

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Codeine Phosphate

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DRUG DESCRIPTION

WARNING - MAY BE HABIT FORMING

Codeine is an alkaloid obtained from opium or prepared from morphine by methylation and occurs as white crystals. Codeine effloresces slowly in dry air and is effected by light. The chemical name of codeine phosphate is 7,8-Didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol phosphate (1:1)(salt) hemihydrate and has the empirical formula of C18H21NO3·H3PO4·1/2H20. Its molecular weight is 406.4.

Each soluble tablet contains 30 mg (0.074 mmol) or 60 mg (0.15 mmol) of codeine phosphate. These tablets also contain lactose and sucrose.

Soluble tablets of codeine phosphate are freely soluble in water. They are intended for the preparation of solutions for parenteral administration. These tablets are not sterile. Codeine phosphate is an analgesic.

What are the possible side effects of codeine ()?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
feeling light-headed, fainting;
confusion, agitation, hallucinations, unusual thoughts or behavior;
seizure (convulsions); or
problems with urination.

Less serious side effects include:

feeling...

Read All Potential Side Effects and See Pictures of Codeine Phosphate »

What are the precautions when taking codeine phosphate (Codeine Phosphate)?

Before using codeine phosphate injection, tell your doctor or pharmacist if you are allergic to it; or to other narcotic pain medications; or if you have any other allergies. This product may contain other inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: abdominal problems (such as chronic constipation, ileus), brain disorders (such as brain injury, tumor, increased intracranial pressure, seizures), diarrhea due to infection (such as Clostridium difficile), breathing problems (such as emphysema, chronic bronchitis, asthma, sleep apnea), heart problems (such as irregular heartbeat, heart failure, low blood pressure),...

Read All Potential Precautions of Codeine Phosphate »

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.