"Nov. 1, 2012 -- Two more drugs made by the New England Compounding Center (NECC) are crawling with various kinds of bacteria, FDA tests reveal.
The NECC is the Massachusetts compounding pharmacy whose drugs are the likely source of th"...
Codeine Phosphate Side Effects Center
Pharmacy Editor: Charles Patrick Davis, MD, PhD
Codeine phosphate is an opioid analgesic (pain reliever) drug used to treat many causes of mild to moderate pain. Codeine phosphate is available in a generic form termed codeine. Common side effects include drowsiness, lightheadedness, and dizziness, and sedation, shortness of breath, nausea, vomiting, sweating, and constipation. The drug may be habit-forming.
Codeine phosphate is available in strengths of 30 and 60mg tablets. Usual adult doses are15 to 60 mg every 4 to 6 hours (usual adult dose, 30 mg), while dosage for children (1 year and older , is weight-based (0.5mg/Kg) every 4 to 6 hours. Serious side effects include dependence, seizures, confusion, near-syncopy, bradycardia and shallow breathing. Codeine sulfate may be expected to have additive effects when used in conjunction with alcohol, other opioids, or illicit drugs that cause central nervous system depression. There are no adequate and well-controlled studies in pregnant women. Codeine should be used during pregnancy only if the potential benefit justifies the potential risk. Codeine is secreted into human milk so benefits should outweigh risks to the breast-feeding infant. Codeine phosphate has been used in pediatric patients aged one year and above.
Our Codeine sulfate Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Codeine Phosphate in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- slow heart rate, weak pulse, fainting, shallow breathing;
- feeling like you might pass out;
- confusion, agitation, hallucinations, unusual thoughts or behavior;
- feelings of extreme happiness or sadness;
- seizure (convulsions); or
- problems with urination.
Less serious side effects include:
- feeling dizzy or drowsy;
- nausea, vomiting, stomach pain,;
- sweating; or
- mild itching or rash.
Read the entire detailed patient monograph for Codeine Phosphate (Codeine Phosphate) »
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Codeine Phosphate FDA Prescribing Information: Side Effects
The most frequent adverse reactions include lightheadedness, dizziness, sedation, nausea, and vomiting. These effects seem to be more prominent in ambulatory than in non ambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.
Drug Abuse and Dependence
Although much less potent in this regard than morphine, codeine can produce drug dependence a.d. therefore, has the potential for being abused. Patients given 60 mg codeine every 6 hours for 2 months usually show some tolerance and mild withdrawal symptoms. Development of the dependent state is recognized by an increased tolerance to the analgesic effect and the appearance of purposive phenomena (complaints, pleas, demands, or manipulative actions) shortly before the time of the next scheduled dose. A patient in withdrawal should be treated in a hospital environment. Usually, it is necessary only to provide supportive care with administration of a tranquilizer to suppress anxiety. Severe symptoms of withdrawal may require administration of a replacement narcotic.
Read the entire FDA prescribing information for Codeine Phosphate (Codeine Phosphate) »
Additional Codeine Phosphate Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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