"Adding opicapone to levodopa therapy in patients with Parkinson's disease (PD) experiencing motor fluctuations reduces "off" time by almost an hour and increases "on" time, without affecting the rate of troublesome dyskinesia, according to "...
(benztropine mesylate) Injection
Benztropine mesylate is a synthetic compound containing structural features found in atropine and diphenhydramine.
It is designated chemically as 8-azabicyclo[3.2.1] octane, 3-(diphenylmethoxy)-,endo, methanesulfonate. Its empirical formula is C21H25NO•CH4O3S, and its structural formula is:
Benztropine mesylate is a crystalline white powder, very soluble in water, and has a molecular weight of 403.54.
COGENTIN (benztropine mesylate) is supplied as a sterile injection for intravenous and intramuscular use.
Each milliliter of the injection contains:
Sodium chloride……………………..9 mg
Water for injection q.s……………..1 mL
What are the possible side effects of benztropine (Cogentin)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- pounding heartbeats or fluttering in your chest;
- feeling very weak;
- feeling too weak to move;
- confusion, hallucinations, unusual thoughts or behavior;
- urinating less than usual or not at all;
- severe constipation;
- dry mouth that interferes with speech, swallowing, appetite, or...
Last reviewed on RxList: 5/3/2013
This monograph has been modified to include the generic and brand name in many instances.
Additional Cogentin Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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