Cola Nut

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Are there any interactions with medications?



Amphetamines
Interaction Rating: Major Do not take this combination.

Stimulant drugs such as amphetamines speed up the nervous system. By speeding up the nervous system, stimulant medications can make you feel jittery and increase your heart rate. The caffeine in cola nut might also speed up the nervous system. Taking caffeine along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with caffeine.



Cocaine
Interaction Rating: Major Do not take this combination.

Stimulant drugs such as cocaine speed up the nervous system. By speeding up the nervous system, stimulant medications can make you feel jittery and increase your heart rate. The caffeine in cola nut might also speed up the nervous system. Taking caffeine along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with cola nut.



Ephedrine
Interaction Rating: Major Do not take this combination.

Stimulant drugs speed up the nervous system. The caffeine in cola nut and ephedrine are both stimulant drugs. Taking caffeine along with ephedrine might cause too much stimulation and sometimes serious side effects and heart problems. Do not take caffeine-containing products and ephedrine at the same time.



Alcohol
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Alcohol can decrease how quickly the body breaks down caffeine. Taking cola nut along with alcohol might cause too much caffeine in the bloodstream and caffeine side effects including jitteriness, headache, and fast heartbeat.



Antibiotics (Quinolone antibiotics)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Some antibiotics might decrease how quickly the body breaks down caffeine. Taking these antibiotics along with cola nut can increase the risk of side effects including jitteriness, headache, increased heart rate, and other side effects.

Some antibiotics that decrease how quickly the body breaks down caffeine include ciprofloxacin (Cipro), enoxacin (Penetrex), norfloxacin (Chibroxin, Noroxin), sparfloxacin (Zagam), trovafloxacin (Trovan), and grepafloxacin (Raxar).



Clozapine (Clozaril)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down clozapine (Clozaril) to get rid of it. The caffeine in cola nut seems to decrease how quickly the body breaks down clozapine (Clozaril). Taking cola nut along with clozapine (Clozaril) can increase the effects and side effects of clozapine (Clozaril).



Dipyridamole (Persantine)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. The caffeine in cola nut might block the effects of dipyridamole (Persantine). Dipyridamole (Persantine) is often used by doctors to do a test on the heart. This test is called a cardiac stress test. Stop consuming cola nut or other caffeine-containing products at least 24 hours before a cardiac stress test.



Disulfiram (Antabuse)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Disulfiram (Antabuse) can decrease how quickly the body gets rid of caffeine. Taking cola nut along with disulfiram (Antabuse) might increase the effects and side effects of caffeine including jitteriness, hyperactivity, irritability, and others.



Estrogens
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Estrogens can decrease how quickly the body breaks down caffeine. Taking estrogens along with cola nut can cause jitteriness, headache, fast heartbeat, and other side effects. If you take estrogens, limit your caffeine intake.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.



Fluvoxamine (Luvox)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Fluvoxamine (Luvox) can decrease how quickly the body breaks down caffeine. Taking caffeine along with fluvoxamine (Luvox) might cause too much caffeine in the body, and increase the effects and side effects of caffeine.



Lithium
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Your body naturally gets rid of lithium. The caffeine in cola nut can increase how quickly your body gets rid of lithium. If you take products that contain caffeine and you take lithium, stop taking caffeine products slowly. Stopping caffeine too quickly can increase the side effects of lithium.



Medications for asthma (Beta-adrenergic agonists)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. Caffeine can stimulate the heart. Some medications for asthma can also stimulate the heart. Taking caffeine with some medications for asthma might cause too much stimulation and cause heart problems.

Some medications for asthma include albuterol (Proventil, Ventolin, Volmax), metaproterenol (Alupent), terbutaline (Bricanyl, Brethine), and isoproterenol (Isuprel).



Medications for depression (MAOIs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. Caffeine can stimulate the body. Some medications used for depression can also stimulate the body. Taking cola nut with these medications used for depression might cause too much stimulation. This could cause serious side effects including fast heartbeat, high blood pressure, nervousness, and others.

Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.



Nicotine
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Stimulant drugs such as nicotine speed up the nervous system. By speeding up the nervous system, stimulant medications can make you feel jittery and increase your heart rate. The caffeine in cola nut might also speed up the nervous system. Taking caffeine along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with caffeine.



Pentobarbital (Nembutal)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The stimulant effects of the caffeine in cola nut can block the sleep-producing effects of pentobarbital.



Phenylpropanolamine
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The caffeine in cola nut can stimulate the body. Phenylpropanolamine can also stimulate the body. Taking cola nut along with phenylpropanolamine might cause too much stimulation and increase heartbeat, blood pressure, and cause nervousness.



Riluzole (Rilutek)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down riluzole (Rilutek) to get rid of it. Taking cola nut can decrease how fast the body breaks down riluzole (Rilutek) and increase the effects and side effects of riluzole.



Theophylline
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. Caffeine works similarly to theophylline. Caffeine can also decrease how quickly the body gets rid of theophylline. Taking cola nut along with theophylline might increase the effects and side effects of theophylline.



Verapamil (Calan, Covera, Isoptin, Verelan)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Verapamil (Calan, Covera, Isoptin, Verelan) can decrease how fast the body gets rid of caffeine. Taking cola nut along with verapamil (Calan, Covera, Isoptin, Verelan) can increase the risk of side effects from caffeine including jitteriness, headache, and an increased heartbeat.



Adenosine (Adenocard)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. The caffeine in cola nut might block the effects of adenosine (Adenocard). Adenosine (Adenocard) is often used by doctors to do a test on the heart. This test is called a cardiac stress test. Stop consuming cola nut or other caffeine-containing products at least 24 hours before a cardiac stress test.



Birth control pills (Contraceptive drugs)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Birth control pills can decrease how quickly the body breaks down caffeine. Taking cola nut along with birth control pills can cause jitteriness, headache, fast heartbeat, and other side effects.

Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others.



Cimetidine (Tagamet)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

The body breaks down the caffeine in cola nut to get rid of it. Cimetidine (Tagamet) can decrease how quickly your body breaks down caffeine. Taking cimetidine (Tagamet) along with cola nut might increase the chance of caffeine side effects including jitteriness, headache, fast heartbeat, and others.



Fluconazole (Diflucan)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. The body breaks down caffeine to get rid of it. Fluconazole (Diflucan) might decrease how quickly the body gets rid of caffeine. This could cause caffeine to stay in the body too long and increase the risk of side effects such as nervousness, anxiety, and insomnia.



Medications for diabetes (Antidiabetes drugs)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Cola nut might increase blood sugar. Diabetes medications are used to lower blood sugar. By increasing blood sugar, cola nut might decrease the effectiveness of diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.



Mexiletine (Mexitil)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. The body breaks down caffeine to get rid of it. Mexiletine (Mexitil) can decrease how quickly the body breaks down caffeine. Taking cola nut along with mexiletine (Mexitil) might increase the effects and side effects of caffeine.



Terbinafine (Lamisil)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Cola nut contains caffeine. The body breaks down the caffeine in cola nut to get rid of it. Terbinafine (Lamisil) can decrease how fast the body gets rid of caffeine. Taking cola nut along with terbinafine (Lamisil) can increase the risk of caffeine side effects including jitteriness, headache, and an increased heartbeat.

Dosing considerations for Cola Nut.

The appropriate dose of cola nut depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for cola nut. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.


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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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