Colchicine
"Gout and hyperuricemia facts
- Painful gouty arthritis is caused by uric-acid-crystal deposits in joint tissue.
- Gout is a chronic, progressive disease.
- The tendency to develop gout and elevated blood uric "...
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Colchicine
Colchicine Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Prescribing Information
- Drug Description
- Indications & Dosage
- Side Effects & Drug Interactions
- Warnings & Precautions
- Overdosage & Contraindications
- Clinical Pharmacology
- Medication Guide
For Patients
Colchicine (Brand: Colcrys) is used to prevent or treat gout attacks (flares), and is also used to prevent attacks of pain in the abdomen, chest, or joints caused by a certain inherited disease (familial Mediterranean fever). It is an alkaloid. Common side effects include diarrhea, nausea, cramping, abdominal pain, and vomiting.
To treat acute gouty arthritis the usual dose of colchicine to relieve or abort an attack is 1 to 1.2 mg (two 0.5 mg granules or two 0.6 mg tablets). This dose may be followed by one unit of either preparation (granule or tablet) every hour, or two units every two hours, until pain is relieved or until diarrhea ensues. Colchicine may interact with azole antifungals, cyclosporine, HIV medications, antibiotics, telithromycin, verapamil, atorvastatin, digoxin, gemfibrozil, fenofibrate, pravastatin, or simvastatin. Tell your doctor all medications and supplements you use. During pregnancy, colchicine should be used only when prescribed. This medication passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breastfeeding. Our Colchicine (Brand: Colcrys) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Colchicine Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Stop taking this medication and seek immediate medical attention if any of these rare but serious side effects occur: unusual bleeding/bruising, severe diarrhea or vomiting, muscle weakness or pain, numbness/tingling in your fingers or toes, pale or gray color of the lips/tongue/palms of hands, signs of infection (such as fever, persistent sore throat), unusual weakness/tiredness.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Colchicine (Colchicine)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Colchicine FDA Prescribing Information: Side Effects
(Adverse Reactions)
SIDE EFFECTS
Adverse reactions in decreasing order of severity are: bone marrow depression, with aplastic anemia, with agranulocytosis or with thrombocytopenia may occur in patients receiving long-term therapy. Peripheral neuritis, purpura, myopathy, loss of hair, and reversible azoospermia have also been reported.
Vomiting, diarrhea, and nausea may occur with colchicine therapy, especially when maximal doses are necessary for a therapeutic effect. To avoid more serious toxicity, the drug should be discontinued when these symptoms appear, regardless of whether or not joint pain has been relieved.
Dermatoses have been reported. Hypersensitivity reactions may occur infrequently.
Read the entire FDA prescribing information for Colchicine (Colchicine) »
Additional Colchicine Information
Colchicine - User Reviews
Colchicine User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Colchicine sorted by most helpful.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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