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Colcrys

What is gout? What is hyperuricemia?

Gout is a disease that results from an overload of uric acid in the body. This overload of uric acid leads to the formation of tiny crystals of urate that deposit in tissues of the body, especially the joints. When crystals form in the joints, it causes recurring attacks of joint inflammation (arthritis). Gout is considered a chronic and progressive disease. Chronic gout can also lead to deposits of hard lumps of uric acid in the tissues, particularly in and around the joints and may cause joint destruction, decreased kidney function, and kidney stones (nephrolithiasis).

Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of p...

Colcrys

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Colcrys Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Colcrys (colchicine, USP) is FDA-approved to treat gout in adults, and to treat a genetic condition called Familial Mediterranean Fever in adults and children who are at least 4 years old. Colchicine was developed prior to federal regulations requiring FDA review of drug products, not all uses for colchicine are approved by the FDA. As of 2009, Colcrys is the only brand of colchicine approved by the FDA. Generic forms of colchicine have been used to treat or prevent attacks of gout, or to treat symptoms of Behcets syndrome (swelling, redness, warmth, and pain). Common side effects include diarrhea, nausea, cramping, abdominal pain, and vomiting.

The dosing regimens for Colcrys are different for each condition being treated, and must be individualized. Colcrys may interact with conivaptan, digoxin, diclofenac, imatinib, isoniazid, quinidine, antidepressants, antibiotics, antifungal medications, cholesterol-lowering medicines, heart or blood pressure medication, HIV or AIDS medication, or medicines used to prevent organ transplant rejection. Tell your doctor all medications you are taking. During pregnancy, Colcrys should be used only when prescribed. This medication passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

Our Colcrys (colchicine, USP) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Colcrys Prescribing Information: Indications & Dosage

Colcrys (colchicine) structural formula illustration

Gout Flares

COLCRYS® (colchicine, USP) tablets are indicated for prophylaxis and the treatment of acute gout flares.

Prophylaxis of Gout Flares

COLCRYS is indicated for prophylaxis of gout flares.

Treatment of Gout Flares

COLCRYS tablets are indicated for treatment of acute gout flares when taken at the first sign of a flare.

Familial Mediterranean fever (FMF)

COLCRYS® (colchicine, USP) tablets are indicated in adults and children 4 years or older for treatment of familial Mediterranean fever (FMF).

Read the complete drug monograph for Colcrys »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Colcrys Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • muscle pain or weakness;
  • numbness or tingly feeling in your fingers or toes;
  • pale or gray appearance of your lips, tongue, or hands;
  • severe vomiting or diarrhea;
  • easy bruising or bleeding, feeling weak or tired;
  • fever, chills, body aches, flu symptoms;
  • blood in your urin...

Read the complete patient information for Colcrys »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Colcrys Consumer Information: Uses

This medication is used to prevent or treat gout attacks (flares). Usually gout symptoms develop suddenly and involve only one or a few joints. The big toe, knee, or ankle joints are most often affected. Gout is caused by too much uric acid in the blood. When uric acid levels in the blood are too high, the uric acid may form hard crystals in your joints. Colchicine works by decreasing swelling and lessening the build up of uric acid crystals that cause pain in the affected joint(s).

This medication is also used to prevent attacks of pain in the abdomen, chest, or joints caused by a certain ...

Read the complete consumer information for Colcrys »

What is Colcrys Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Colcrys - User Reviews

Colcrys User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Colcrys sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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