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Gout is a disease that results from an overload of uric acid in the body. This overload of uric acid leads to the formation of tiny crystals of urate that deposit in tissues of the body, especially the joints. When crystals form in the joints, it causes recurring attacks of joint inflammation (arthritis). Gout is considered a chronic and progressive disease. Chronic gout can also lead to deposits of hard lumps of uric acid in the tissues, particularly in and around the joints and may cause joint destruction, decreased kidney function, and kidney stones (nephrolithiasis).
Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of p...
Medical Editor: John P. Cunha, DO, FACOEP
Colcrys (colchicine, USP) is FDA-approved to treat gout in adults, and to treat a genetic condition called Familial Mediterranean Fever in adults and children who are at least 4 years old. Colchicine was developed prior to federal regulations requiring FDA review of drug products, not all uses for colchicine are approved by the FDA. As of 2009, Colcrys is the only brand of colchicine approved by the FDA. Generic forms of colchicine have been used to treat or prevent attacks of gout, or to treat symptoms of Behcets syndrome (swelling, redness, warmth, and pain). Common side effects include diarrhea, nausea, cramping, abdominal pain, and vomiting.
The dosing regimens for Colcrys are different for each condition being treated, and must be individualized. Colcrys may interact with conivaptan, digoxin, diclofenac, imatinib, isoniazid, quinidine, antidepressants, antibiotics, antifungal medications, cholesterol-lowering medicines, heart or blood pressure medication, HIV or AIDS medication, or medicines used to prevent organ transplant rejection. Tell your doctor all medications you are taking. During pregnancy, Colcrys should be used only when prescribed. This medication passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.
Our Colcrys (colchicine, USP) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
COLCRYS® (colchicine, USP) tablets are indicated for prophylaxis and the treatment of acute gout flares.
COLCRYS is indicated for prophylaxis of gout flares.
COLCRYS tablets are indicated for treatment of acute gout flares when taken at the first sign of a flare.
COLCRYS® (colchicine, USP) tablets are indicated in adults and children 4 years or older for treatment of familial Mediterranean fever (FMF).
Read the complete drug monograph for Colcrys »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Read the complete patient information for Colcrys »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
This medication is also used to prevent attacks of pain in the abdomen, chest, or joints caused by a certain ...
Read the complete consumer information for Colcrys »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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