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home > drugs a-z list > coly-mycin m (colistimethate injection) drug center > coly-mycin m (colistimethate injection) drug - overdosage and contraindications
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Coly-Mycin
Pneumonia facts
- Pneumonia is a lung infection that can be caused by different types of microorganisms, including bacteria, viruses, and fungi.
- Symptoms of pneumonia include cough with sputum production, fever, and sharp chest pain on inspiration (breathing in).
- Pneumonia is suspected when a doctor hears abnormal sounds in the chest, and the diagnosis is confirmed by a chest X-ray.
- Bacteria causing pneumonia can be identified by sputum culture.
- A pleural effusion is a fluid collection around the inflamed lung.
- Bacterial and fungal (but not viral) pneumonia can be treated with antibiotics.
What is pneumonia?
Pneumonia is an infection of one or both lungs which is usually caused by bacteria, viruses, or fungi. Prior to the discovery of antibiotics, one-third of all people who developed pneumonia subsequently died fro...
Coly-Mycin M
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OVERDOSE
Overdosage with colistimethate sodium can cause neuromuscular blockade characterized by paresthesia, lethargy, confusion, dizziness, ataxia, nystagmus, disorders of speech and apnea. Respiratory muscle paralysis may lead to apnea, respiratory arrest and death. Overdosage with the drug can also cause acute renal failure, manifested as decreased urine output and increases in serum concentrations of BUN and creatinine.
As in any case of overdose, colistimethate sodium therapy should be discontinued and general supportive measures should be utilized.
It is unknown whether colistimethate sodium can be removed by hemodialysis or peritoneal dialysis in overdose cases.
CONTRAINDICATIONS
The use of Coly-Mycin M (colistimethate injection) Parenteral is contraindicated for patients with a history of sensitivity to the drug or any of its components.
Last reviewed on RxList: 7/27/2009
This monograph has been modified to include the generic and brand name in many instances.
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