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Pneumonia is an infection of one or both lungs which is usually caused by bacteria, viruses, or fungi. Prior to the discovery of antibiotics, one-third of all people who developed pneumonia subsequently died fro...
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The following adverse reactions have been reported:
Gastrointestinal: gastrointestinal upset
Nervous System: tingling of extremities and tongue, slurred speech, dizziness, vertigo and paresthesia
Integumentary: generalized itching, urticaria and rash
Body as a Whole: fever
Laboratory Deviations: increased blood urea nitrogen (BUN), elevated creatinine and decreased creatinine clearance
Respiratory System:respiratory distress and apnea
Renal System: nephrotoxicity and decreased urine output
Certain other antibiotics (aminoglycosides and polymyxin) have also been reported to interfere with the nerve transmission at the neuromuscular junction. Based on this reported activity, they should not be given concomitantly with Coly-Mycin M (colistimethate injection) Parenteral except with the greatest caution.
Curariform muscle relaxants (e.g., tubocurarine) and other drugs, including ether, succinylcholine, gallamine, decamethonium and sodium citrate, potentiate the neuromuscular blocking effect and should be used with extreme caution in patients being treated with Coly-Mycin M (colistimethate injection) Parenteral.
Sodium cephalothin may enhance the nephrotoxicity of Coly-Mycin M (colistimethate injection) Parenteral. The concomitant use of sodium cephalothin and Coly-Mycin M (colistimethate injection) Parenteral should be avoided.
Last reviewed on RxList: 7/27/2009
This monograph has been modified to include the generic and brand name in many instances.
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