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Combigan

"Glaucoma is a group of diseases that damage the optic nerve, a cable at the back of each eye that connects it to the brain. It affects more than 2.7 million people in the United States and more than 60 million worldwide. There are many forms of t"...

Combigan

Indications
Dosage
How Supplied

INDICATIONS

COMBIGAN® (brimonidine tartrate/timolol maleate) Ophthalmic Solution 0.2%/0.5% is an alpha-adrenergic receptor agonist with a beta-adrenergic receptor inhibitor indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP; the IOP-lowering of COMBIGAN® dosed twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol maleate ophthalmic solution dosed twice a day and 0.2% brimonidine tartrate ophthalmic solution dosed three times per day.

DOSAGE AND ADMINISTRATION

The recommended dose is one drop of COMBIGAN® in the affected eye(s) twice daily approximately 12 hours apart. If more than one topical ophthalmic product is to be used, the different products should be instilled at least 5 minutes apart.

HOW SUPPLIED

Dosage Forms And Strengths

Solution containing 2 mg/mL brimonidine tartrate and 5 mg/mL timolol (6.8 mg/mL timolol maleate).

Storage And Handling

COMBIGAN® is supplied sterile, in white opaque plastic LDPE bottles and tips, with blue high impact polystyrene (HIPS) caps as follows:

5 mL in 10 mL bottle NDC 0023-9211-05
10 mL in 10 mL bottle NDC 0023-9211-10

Storage

Store at 15°- 25°C (59°-77°F). Protect from light.

Allergan, Inc., Irvine, CA 92612, U.S.A. Revised: 10/2012

Last reviewed on RxList: 10/19/2012
This monograph has been modified to include the generic and brand name in many instances.

Indications
Dosage
How Supplied
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