"Consumers and health care professionals will soon find updated labeling for extended-release and long-acting opioid pain relievers to help ensure their safe and appropriate use.
In addition to requiring new labeling on these prescript"...
Combunox Patient Information including If I Miss a Dose
In this Article
- What is ibuprofen and oxycodone (Combunox)?
- What are the possible side effects of ibuprofen and oxycodone (Combunox)?
- What is the most important information I should know about ibuprofen and oxycodone (Combunox)?
- What should I discuss with my healthcare provider before taking ibuprofen and oxycodone (Combunox)?
- How should I take ibuprofen and oxycodone (Combunox)?
- What happens if I miss a dose (Combunox)?
- What happens if I overdose (Combunox)?
- What should I avoid while taking ibuprofen and oxycodone (Combunox)?
- What other drugs will affect ibuprofen and oxycodone (Combunox)?
- Where can I get more information?
What happens if I miss a dose (Combunox)?
Since ibuprofen and oxycodone is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Combunox)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of ibuprofen and oxycodone can be fatal.
Overdose symptoms may include extreme drowsiness, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), black or bloody stools, coughing up blood, urinating less than usual or not at all, confusion, ringing in your ears, pinpoint pupils, weak pulse, slow heart rate, fainting, blue lips, shallow breathing.
What should I avoid while taking ibuprofen and oxycodone (Combunox)?
This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how ibuprofen and oxycodone will affect you.
Ask a doctor or pharmacist before using any other cold, allergy, or pain medicine. Ibuprofen is contained in many combination medicines. Taking certain products together can cause you to get too much ibuprofen. Check the label to see if a medicine contains ibuprofen.
Avoid drinking alcohol. It may increase your risk of stomach bleeding.
What other drugs will affect ibuprofen and oxycodone (Combunox)?
Before using this medicine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, other narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by oxycodone.
Also tell your doctor if you are using any of the following drugs:
- a blood thinner such as warfarin (Coumadin, Jantoven);
- a diuretic (water pill);
- an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);
- aspirin or other NSAIDs such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;
- heart or blood pressure medication such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others;
- lithium (Eskalith, Lithobid);
- a bronchodilator (such as Atrovent, Spiriva), diuretics (water pills), steroid medicines, or blood thinners;
- methotrexate (Rheumatrex, Trexall);
- an injected narcotic medicine such as pentazocine (Talwin), butorphanol (Stadol), or nalbuphine Nubain);
- atropine (Donnatal), dimenhydrinate (Dramamine), or scopolamine (Transderm-Scop); or
- bowel or bladder medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin), tolterodine (Detrol) and others;
This list is not complete and other drugs may interact with ibuprofen and oxycodone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about ibuprofen and oxycodone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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