Compazine (Prochlorperazine) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 26, 2012

Compazine

Nausea and Vomiting »

Nausea and vomiting facts

Nausea and vomiting are symptoms of a disease or condition. The underlying cause of the illness causing nausea and vomiting should be identified and treated.
Nausea and vomiting symptom control is important both for comfort's sake and to prevent dehydration.
Dehydration can worsen nausea and vomiting.
Medication may be available to control symptoms of nausea and vomiting.

Introduction to nausea and vomiting

Nausea and vomiting are symptoms of an underlying illness and not a specific disease. Nausea is the sensation that the stomach wants to empty itself, while vomiting (emesis) or throwing up, is the act of forcible emptying of the stomach. The term "dry heaves" refers to an episode of vomiting where there is no food in the stomach to vomit, and only clear secretions are vomited.

Vomiting is a violent act in which the stomach almost...

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Compazine

Schizophrenia Slideshow Pictures

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Compazine Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Prescribing Information

For Patients

Compazine in Detail with Side Effects

Compazine (prochlorperazine) is used to treat psychotic disorders such as schizophrenia. It is also used to treat anxiety, and to control severe nausea and vomiting. It is a phenothiazine anti-psychotic. The brand name Compazine is discontinued in the U.S. Generic versions may still be available. Common side effects include dizziness, drowsiness, anxiety, sleep problems (insomnia), strange dreams, dry mouth, stuffy nose, blurred vision, constipation, breast swelling or discharge, missed menstrual period, weight gain, swelling in hands or feet, impotence, trouble having an orgasm, mild itching, skin rash, or headache.

Dosage of prochlorperazine is adjusted to the response of the individual. Begin with the lowest recommended dosage. Prochlorperazine may interact with atropine, lithium, diuretics (water pills), antibiotics, birth control pills or hormone replacement estrogens, blood pressure medications, blood thinners, asthma medications, drugs to treat prostate disorders, incontinence medications, insulin or oral diabetes medications, medication for nausea, vomiting, or motion sickness, medications to treat or prevent malaria, medications used for general anesthesia, medicines used to prevent organ transplant rejection, numbing medicine, stimulants, ADHD medication, ulcer or irritable bowel medications, medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor. Many other medicines can interact with prochlorperazine. Tell your doctor all medications you use. During pregnancy, prochlorperazine should be used only if prescribed. It may cause side effects in a newborn if the mother takes the medication during pregnancy. This medication can pass into breast milk and may harm a nursing baby. Consult your doctor before breast-feeding.

Our Compazine (prochlorperazine) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Compazine Prescribing Information: Indications & Dosage

COMPAZINE® (prochlorperazine) Structural Formula Illustration

For control of severe nausea and vomiting.

For the treatment of schizophrenia.

Compazine (prochlorperazine) is effective for the short-term treatment of generalized non-psychotic anxiety. However, Compazine (prochlorperazine) is not the first drug to be used in therapy for most patients with non-psychotic anxiety, because certain risks associated with its use are not shared by common alternative treatments (e.g., benzodiazepines).

When used in the treatment of non-psychotic anxiety, Compazine (prochlorperazine) should not be admini...

Read the complete drug monograph for Compazine »

What is Compazine Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Compazine Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using prochlorperazine and call your doctor at once if you have a serious side effect such as:

twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
tremor (uncontrolled shaking), drooling, trouble swallowing, problems with balance or walking;
feeling restless, jittery, or agitated;
high fever, stiff muscles, confusion, sweating, fast ...

Read the complete patient information for Compazine »