April 30, 2017
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Complera Patient Information including If I Miss a Dose

What happens if I miss a dose (Complera)?

If you are less than 12 hours late in taking your medicine, take the missed dose as soon as you remember. Be sure to take the medicine with a meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Complera)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking emtricitabine, rilpivirine, and tenofovir (Complera)?

If you also take an antacid, take it at least 2 hours before or 4 hours after taking emtricitabine, rilpivirine, and tenofovir.

If you also take a heartburn or GERD medicine (such as Tagamet, Pepcid, Axid, or Zantac), take it at least 12 hours before or 4 hours after taking emtricitabine, rilpivirine, and tenofovir.

Taking this medication will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

What other drugs will affect emtricitabine, rilpivirine, and tenofovir (Complera)?

This medication can harm your kidneys. This effect is increased when you also use other medicines harmful to the kidneys. You may need dose adjustments or special tests if you have recently used:

  • medicines to treat a bowel disorder;
  • medication to prevent organ transplant rejection;
  • chemotherapy;
  • other antiviral medications (including medicines to treat herpes or cytomegalovirus (CMV);
  • pain or arthritis medicines; or
  • injected (IV) antibiotics.

There are many other drugs that can interact with emtricitabine, rilpivirine, and tenofovir. Below is just a partial list. Tell your doctor if you are using:

  • antibiotics or antifungal medications;
  • an antidepressant;
  • anti-malaria medication;
  • heart or blood pressure medication;
  • medicines to treat narcolepsy;
  • medicine to prevent or treat nausea and vomiting;
  • medicines to treat psychiatric disorders;
  • many other HIV medicines;
  • migraine headache medication; or
  • narcotic medication.

This list is not complete and other drugs may interact with emtricitabine, rilpivirine, and tenofovir. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about emtricitabine, rilpivirine, and tenofovir.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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