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Complera

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Complera

Complera Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking emtricitabine, rilpivirine, and tenofovir (Complera)?

You should not take this medication if you are allergic to emtricitabine (Emtriva), rilpivirine (Edurant), or tenofovir (Viread).

Do not take this medication with other medicines that also contain emtricitabine, rilpivirine, or tenofovir (Atripla, Edurant, Emtriva, Truvada, Viread), or adefovir or lamivudine (Combivir, Epivir, Epzicom, Hepsera, or Trizivir).

There are many other drugs that can make rilpivirine less effective. The following drugs should not be used together with emtricitabine, rilpivirine, and tenofovir:

  • dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
  • St. John's wort;
  • rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
  • the seizure medicines carbamazepine (Carbatrol, Equetro, Tegretol), oxcarbazepine (Trileptal), phenobarbital (Solfoton), or phenytoin (Dilantin); or
  • stomach acid reducers such as esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), or rabeprazole (AcipHex).

To make sure you can safely take emtricitabine, rilpivirine, and tenofovir, tell your doctor if you have any of these other conditions:

  • kidney disease;
  • osteopenia (low bone mineral density);
  • a personal or family history of Long QT syndrome; or
  • if you also have hepatitis B infection.

Some people develop a life-threatening condition called lactic acidosis while taking tenofovir. You may be more likely to develop lactic acidosis if you are overweight or have liver disease, if you are a woman, or if you have taken HIV or AIDS medications for a long time. Talk with your doctor about your individual risk.

FDA pregnancy category B. Emtricitabine, rilpivirine, and tenofovir is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of emtricitabine, rilpivirine, and tenofovir on the baby.

Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Do not give this medicine to anyone under 18 without the advice of a doctor.

How should I take emtricitabine, rilpivirine, and tenofovir (Complera)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Emtricitabine, rilpivirine, and tenofovir is usually taken once per day with a meal. Follow your doctor's instructions.

Use emtricitabine, rilpivirine, and tenofovir regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

To be sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Your kidney and liver function or bone density may also need to be tested. Visit your doctor regularly.

If you have hepatitis B you may develop liver symptoms after you stop taking this medication, even months after stopping. Your doctor may want to check your liver function for several months after you stop using emtricitabine, rilpivirine, and tenofovir. Visit your doctor regularly.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

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