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(prochlorperazine) Suppositories, USP 25mg



Prochlorperazine is a clear, pale yellow, viscous liquid. It is sensitive to light, very slightly soluble in water, freely soluble in alcohol, in chloroform, and in ether.

Each suppository, for rectal administration, contains 25mg of prochlorperazine; with glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids and hydrogenated palm kernel oil fatty acids.

Prochlorperazine has the molecular formula C20H24ClN3S. Its molecular weight is 373.95. The chemical name for prochlorperazine is 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl] phenothiazine.

What are the possible side effects of rectal prochlorperazine (Compro)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using prochlorperazine and call your doctor at once if you have a serious side effect such as:

  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
  • tremor (uncontrolled shaking), drooling, trouble swallowing, problems with balance or walking;
  • high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid...

Read All Potential Side Effects and See Pictures of Compro »

Last reviewed on RxList: 8/13/2008
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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