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In this Article

• What is methylphenidate (Concerta)?
• What are the possible side effects of methylphenidate?
• What is the most important information I should know about methylphenidate?
• What should I discuss with my healthcare provider before taking methylphenidate?
• How should I take methylphenidate?
• What happens if I miss a dose?
• What happens if I overdose?
• What should I avoid while taking methylphenidate?
• What other drugs will affect methylphenidate?
• Where can I get more information?

What should I discuss with my healthcare provider before taking methylphenidate?

Do not take methylphenidate if you have used an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam) within the past 14 days. Serious, life-threatening side effects can occur if you use methylphenidate before the MAO inhibitor has cleared from your body.

Do not use this medication if you are allergic to methylphenidate or if you have:

• glaucoma;
• overactive thyroid;
• severe high blood pressure;
• angina (chest pain), heart failure, heart rhythm disorder, or recent heart attack;
• a personal or family history of tics (muscle twitches) or Tourette's syndrome;
• severe anxiety, tension, or agitation (methylphenidate can make these symptoms worse); or
• a hereditary condition such as fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency.

Some stimulants have caused sudden death in children and adolescents with serious heart problems or congenital heart defects. Tell your doctor if you have a congenital heart defect.

If you have certain other conditions, you may need a dose adjustment or special tests to safely take this medication. Before using methylphenidate, tell your doctor if you are allergic to any drugs, or if you have:

• a congenital heart defect;
• a personal or family history of mental illness, psychotic disorder, bipolar illness, depression, or suicide attempt;
• epilepsy or other seizure disorder; or
• a history of drug or alcohol addiction.

FDA pregnancy category C. It is not known whether methylphenidate is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether methylphenidate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Long-term use of methylphenidate can slow a child's growth. Tell your doctor if the child using this medication is not growing or gaining weight properly.

Do not give methylphenidate to a child younger than 6 years old without the advice of a doctor.

How should I take methylphenidate?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medication at least 30 minutes before a meal. The extended-release forms of methylphenidate (Ritalin-SR, Metadate ER, Metadate CD, Methylin ER, Concerta) can be taken with or without food.

The chewable tablet must be chewed before you swallow it.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

If you have trouble swallowing the extended-release capsule, you may open the capsule and sprinkle the medicine into a spoonful of applesauce to make swallowing easier. Swallow this mixture right away without chewing. Do not save the mixture for later use. Discard the empty capsule.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To prevent sleep problems, take this medication early in the day, no later than 6:00 pm.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using methylphenidate. You may need to stop using the medicine the day of your surgery.

Store methylphenidate at room temperature away from moisture and heat.

Keep track of how many pills have been used from each new bottle of this medicine. Methylphenidate is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.