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Condylox® Gel 0.5%
Podofilox is an antimitotic drug which can be chemically synthesized or purified from the plant families Coniferae and Berberidaceae ( e.g. species of Juniperus and Podophyllum). Condylox Gel (podofilox gel) 0.5% is formulated for topical administration. Each gram of gel contains 5 mg of podofilox in a buffered alcoholic gel containing alcohol, glycerin, lactic acid, hydroxypropyl cellulose, sodium lactate, and butylated hydroxytoluene.
Podofilox has a molecular weight of 414.4 daltons, and is soluble in alcohol and sparingly soluble in water. Its chemical name is [5R,-(5α, 5aβ, 8aα, 9α]-5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl) furo[3',4':6,7]naphtho-[2,3,-d]-1,3-dioxol-6(5aH)-one.
Podofilox has the following structural formula:
What are the possible side effects of podofilox topical (Condylox)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Wash off the medicine and call your doctor at once if you have a serious skin reaction such as severe itching, burning, oozing, bleeding, or skin changes where the medicine is applied.
Less serious side effects may include:
- mild skin irritation, tenderness, bleeding, dryness, peeling, tingling, scarring, blistering, crusting, or swelling of the skin where the medicine was applied;
What are the precautions when taking podofilox gel (Condylox Gel)?
Before taking podofilox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: other skin problems (e.g., skin cancer).
This medication must not be used during pregnancy. Women of child-bearing age should use a reliable form of birth control while using this medication. If you become pregnant or think you may be pregnant, inform your doctor immediately.
It is unknown if this drug passes into breast milk. Consult your doctor before...
Last reviewed on RxList: 11/24/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Condylox Gel Information
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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