Acetylcholine

Brand Name: Miochol E

Generic Name: acetylcholine

Drug Class: Miotics, Direct-Acting

What Is Acetylcholine and How Does It Work?

Acetylcholine is a prescription drug used as a parasympathomimetic preparation for intraocular use.

Acetylcholine is available under the following different brand names: Miochol E.

Dosages of Acetylcholine :

Powder for injection

• 20 mg

Safety and efficacy not established for pediatric use.

Dosing considerations:

• Miosis during Ocular Surgery
• 0.5-2 ml of 1% solution intraocular instillation during surgery
• Administration
• Reconstitute vial with 2 ml supplied diluent to obtain 1% solution; use immediately
• Instill gently into anterior chamber of eye with suitable atraumatic cannula
• May use 2% pilocarpine or 0.25% physostigmine topically immediately after surgery before application of dressing to maintain miosis
• For cataract surgery, instill only after delivery of lens
• Gel
• Children over 12 years: 30 mg every 6-8 hours, not to exceed 120 mg per day
• Lozenges
• Children 6-12 years: 5-10 mg every 1-4 hours, not to exceed 60 mg per day
• Children over 12 years: 5-15 mg orally every 1-4 hours, not to exceed 120 mg per day
• Strips
• Children 6-12 years: 15 mg orally every 6-8 hours, not to exceed 60 mg per day
• Children over 12 years: 30 mg orally every 6-8 hours, not to exceed 120 mg per day
• Dosing Considerations
• Potential toxic doses children under 6 years: 10 mg/kg
• About 15-30 mg acetylcholine is equal to 8-15 mg codeine as an antitussive