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Medical and Pharmacy Editor:

Brand Name: Nuvigil

Generic Name: Armodafinil

Drug Class: Stimulants

What Is Armodafinil and How Does It Work?

Armodafinil is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases as you age, after menopause, or if you are taking corticosteroid medications (such as prednisone) for a long time.

Armodafinil works by slowing bone loss. This effect helps maintain strong bones and reduce the risk of broken bones (fractures). Armodafinil belongs to a class of drugs called bisphosphonates.

Armodafinil is available under the following different brand names: Fosamax, Binosto, and Fosamax Plus D.

Dosages of Armodafinil:

Dosage Forms and Strengths

Tablet: Schedule IV

  • 50 mg
  • 150 mg
  • 200 mg
  • 250 mg

Dosage Considerations – Should be Given as Follows:

Obstructive Sleep Apnea/Hypopnea Syndrome

  • 150-250 mg orally in the morning


  • 150-250 mg orally in the morning

Shift Work Sleep Disorder

  • 150 mg orally once/day 1 hour prior to patient's work shift

Limitation of Use

  • In obstructive sleep apnea, indicated to treat excessive sleepiness and not as treatment for the underlying obstruction

Dosing Modifications

  • Hepatic impairment: Reduce dose
  • Renal impairment: Safety and efficacy not established
  • Pediatric: Safety and efficacy not established
  • Geriatric: Consider lower initial dose
Medically Reviewed by a Doctor on 8/11/2017

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