Buprenorphine (cont.)

What Other Drugs Interact with Buprenorphine?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Severe interactions of buprenorphine include:

• alvimopan

Buprenorphine has serious interactions with at least 42 different drugs.

Buprenorphine has moderate interactions with at least 195 different drugs.

Mild Interactions of buprenorphine include:

• brimonidine
• dextroamphetamine
• elvitegravir
• eucalyptus
• lidocaine
• sage
• ziconotide

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.