Codeine (cont.)

What Other Drugs Interact with Codeine?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Severe Interactions of Codeine include:

• alvimopan

Codeine has serious interactions with at least 22 different drugs.

Codeine has moderate interactions with at least 220 different drugs.

Codeine has minor interactions with at least 23 different drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.