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Dextrose

Medical and Pharmacy Editor:

Brand Name: D50W, DGlucose, Glucose

Generic Name: Dextrose

Drug Class: Glucose-Elevating Agents; Metabolic and Endocrine, Other

What Is Dextrose and How Does It Work?

Dextrose is a prescription sterile, nonpyrogenic solution for fluid replenishment and caloric supply for intravenous and/or oral administration and as treatment of low blood sugar (hypoglycemia).

Dextrose is available under the following different brand names: D50W, DGlucose, and Glucose.

Dosages of Dextrose:

Adult and Pediatric Dosages

Intravenous solution

  • 2.5%
  • 5%
  • 10%
  • 20%
  • 30%
  • 50%
  • 70%

Oral liquid

  • 55%

Dosage Considerations – Should be Given as Follows:

Adults

Low blood sugar (Hypoglycemia)

  • Intravenously: 10-25 g (20-50 ml 50% solution or 40-100 ml of 25%)
  • Orally: 4-20 g as a single dose; may repeat after 15 minutes if self-monitoring of blood glucose shows continued hypoglycemia

Pediatrics

  • Dilute before intravenous (IV) administration, may give more concentrated solution peripherally in emergency (12.5-25%)
  • Infants under 6 months:
    • 0.25-0.5 g/kg/dose (1-2 ml/kg/dose of 25% solution) intravenously; not to exceed 25 g/dose
  • Infants over 6 months and children:
    • 0.5-1 g/kg up to 25 g (2-4 ml/kg/dose of 25% solution) intravenously; not to exceed 25 g/dose
  • Adolescents
    • Intravenously: 10-25 g (20-50 ml 50% solution or 40-100 ml of 25%)
    • Orally: 4-20 g as a single dose; may repeat after 15 minutes if self-monitoring of blood glucose shows continued hypoglycemia
Medically Reviewed by a Doctor on 5/15/2017



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