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Prednisolone

Medical and Pharmacy Editor:

Brand Name: Pediapred, FloPred, Orapred, Orapred ODT, Millipred, Millipred DP, Prelone Syrup, Veripred 20

Generic Name: Prednisolone

Drug Class: Corticosteroids

What Is Prednisolone and How Does It Work?

Prednisolone is a prescription medication indicated in treatment of endocrine disorders, rheumatic disorders, collagen diseases, dermatologic disease, allergic states, ophthalmic diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, gastrointestinal disease, and diseases affecting the nervous system.

Prednisolone is available under the following different brand names: Pediapred, FloPred, Orapred, Orapred ODT, Millipred, Millipred DP, Prelone Syrup, and Veripred 20.

Dosage of Prednisolone:

Adult and Pediatric Dosages:

Oral Solution

  • 5 mg/5 ml
  • 10 mg/5 ml
  • 15 mg/5 ml
  • 20 mg/5 ml
  • 25 mg/5 ml

Tablet

  • 5 mg

Tablet, dose pack

  • 5 mg (6 days [21 tablets])
  • 5 mg (12 days [48 tablets])

Tablet, orally disintegrating

  • 10 mg
  • 15 mg
  • 30 mg

Dosing Considerations – Should be Given as Follows:

Adult Dosage Considerations:

Rheumatoid Arthritis

  • 5.75 mg orally each day

Multiple Sclerosis

  • 200 mg/day orally for 1 week, then 80 mg orally every other day for 1 month

Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) (off label)

  • 30-40 mg orally daily for 10-14 days

Bell's Palsy (off label)

  • 60 mg orally for 5 days; then taper down by 10 mg daily for 5 days for total duration time of 10 days

Pediatric Dosage Considerations:

Inflammation

  • 0.1-2 mg/kg/day orally in single daily dose or divided every 6-12 hours; not to exceed 80 mg/day

Acute Asthma

  • 1-2 mg/kg/day in single daily dose or divided every 12 hours for 3-5 days

Nephrotic Syndrome

  • First 4 weeks: 60 mg/mē/day or 2 mg/kg/day orally divided every 8 hours until urine is protein free for 3 consecutive days; not to exceed 28 days; dose not to exceed 80 mg/day Subsequent 4 weeks: 40 mg/mē or 1-1.5 mg/kg orally every other day; not to exceed 80 mg/day Maintenance in frequent relapses: 0.5-1 mg/kg/dose orally every other day for 3-6 months. Treatment may have to be individualized
Medically Reviewed by a Doctor on 6/9/2017



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