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Sucralfate

Medical and Pharmacy Editor:

Brand Name: Carafate

Generic Name: Sucralfate

Drug Class: Gastrointestinal Agents, Other

What Is Sucralfate and How Does It Work?

Sucralfate is indicated for short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by X-ray or endoscopic examination.

Sucralfate is also indicated for maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.

Sucralfate is available under the following different brand names: Carafate.

Dosages of Sucralfate:

Dosage Forms and Strengths

Tablet

  • 1 g

Oral suspension

  • 1000 mg/10mL

Dosage Considerations – Should be Given as Follows:

Duodenal Ulcer

  • Adult: 1 g orally every 6 hours initially; maintenance: 1 g orally every 12 hours
  • Take on empty stomach 1 hour before or 2 hours after meals
  • Pediatric (Off-label): 40-80 mg/kg/day orally divided every 6 hours

Stress Ulcer (Off-label)

  • Prophylaxis
  • 1 g orally every 6 hours for 4-8 weeks
  • Take on empty stomach 1 hour before or 2 hours after meals

Stomatitis, Pediatric (Off-label)

  • 500-1000 mg orally every 6 hours; 1g/10mL suspension every 6 hours; swish and spit or swish and swallow the suspension

Gastric Ulcer, Pediatric (Off-label)

  • 40-80 mg/kg/day orally divided every 6 hours or 0.5-1 g orally every 6 hours

Dosing Modifications

  • Renal failure: Use with caution; aluminum salt may accumulate
Medically Reviewed by a Doctor on 9/5/2017



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