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Terazosin

Medical and Pharmacy Editor:

Brand Name: Hytrin

Generic Name: Terazosin

Drug Class: Alpha Blockers, Antihypertensive; BPH, Alpha Blockers

What Is Terazosin and How Does It Work?

Terazosin is a prescription drug used as an alpha-adrenergic blocker to treat high blood pressure and enlarged prostate.

Terazosin is available under the following different brand names: Hytrin.

Dosages of Terazosin:

Adult and Pediatric Dosages

Capsules

  • 1 mg
  • 2 mg
  • 5 mg
  • 10 mg

Dosage Considerations – Should be Given as Follows:

Benign Prostate Hyperplasia (BPH)

Adults

  • Initial: 1 mg orally at bedtime; up to 20 mg/day beneficial for some
  • Dosing considerations
    • Give first dose and subsequent increases at bedtime to avoid fainting (syncope)
    • May take with food

Hypertension

  • Adult dosage:
  • Initial: 1 mg orally at bedtime
  • Maintenance: 1-5 mg/day or every 12 hours; may increase up to 20 mg/day
  • Dosing considerations
    • Give first dose and subsequent increases at bedtime to avoid fainting (syncope)
    • May take with food

Geriatric Dosage:

  • Initial: 0.5 mg orally at bedtime and titrate to response
  • Dosing considerations
  • Avoid use for hypertension; high risk of orthostatic hypotension (Beers criteria)
  • May cause significant orthostatic hypotension and fainting
  • Lower initial doses than those used for non-geriatric adults, as well as gradual adjustments, are recommended for hypertension
  • Give first dose and subsequent increases at bedtime to avoid fainting
  • Adverse effects such as dry mouth and urinary complications can be bothersome in the elderly
  • May take with food.

Pediatrics

  • 1 mg/day orally; increase dose gradually as necessary; up to a maximum of 20 mg/day

Dosing Modifications

Hepatic impairment: use with caution

Medically Reviewed by a Doctor on 5/15/2017



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