Slideshows Images Quizzes
font size


Tiotropium

Medical and Pharmacy Editor:

Brand Name: Spiriva HandiHaler, Spiriva Respimat

Generic Name: Tiotropium

Drug Class: Anticholinergics, Respiratory

What Is Tiotropium and How Does It Work?

Tiotropium is used to control and prevent symptoms (such as wheezing, shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema). It works by relaxing the muscles around the airways so that they open up and you can breathe more easily. Tiotropium belongs to a class of drugs known as anticholinergics. Controlling symptoms of breathing problems can decrease time lost from work or school.

Tiotropium must be used regularly to be effective. It does not work right away and should not be used to relieve sudden breathing problems. If wheezing or sudden shortness of breath occurs, use your quick-relief inhaler (such as albuterol, also called salbutamol in some countries) as prescribed.

Tiotropium is available under the following different brand names: Spiriva HandiHaler and Spiriva Respimat.

Dosages of Tiotropium:

Dosage Forms and Strengths

Capsule (Spiriva Handihaler; powder for oral inhalation)

  • 18 mcg

Solution for inhalation (Spiriva Respimat)

  • 1.25 mcg/actuation (adult and pediatric)
  • 2.5 mcg/actuation

Dosage Considerations – Should be Given as Follows:

Chronic Obstructive Pulmonary Disease

  • Maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD); reduction of COPD exacerbations
  • Spiriva Handihaler: 2 orally inhalations of 1 capsule (18 mcg) once/day via HandiHaler inhalation device
  • Spiriva Respimat: 5 mcg (2 actuations; 2.5 mcg/actuation) inhaled orally once/day

Asthma

  • Indicated for long-term, once-daily, maintenance treatment of asthma in patients aged 12 years or older
  • Spiriva Respimat: 2.5 mcg (2 actuations; 1.25 mcg/actuation) inhaled orally once/day

Pediatric:

  • Indicated for long-term, once-daily, maintenance treatment of asthma in patients aged 6 years or older
  • Spiriva Respimat: 2.5 mcg (2 actuations; 1.25 mcg/actuation) inhaled orally once/day

Dosage Modifications

  • CrCl less than 50 mL/min: Use only if benefit outweighs potential risk
Medically Reviewed by a Doctor on 6/15/2017



Women's Health

Find out what women really need.

Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations

Health Solutions From Our Sponsors