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Torsemide

Medical and Pharmacy Editor:

Brand Name: Demadex

Generic Name: Torsemide

Drug Class: Diuretics, Loop

What Is Torsemide and How Does It Work?

Torsemide is a diuretic used to reduce edema (swelling) from multiple causes such as heart failure, renal disease, or liver disease. Use of torsemide has been found to be effective for the treatment of edema associated with chronic renal failure.

Torsemide tablets are also indicated for the treatment of high blood pressure (hypertension) alone or in combination with other antihypertensive agents.

Torsemide is available under the following different brand names: Demadex.

Dosages of Torsemide:

Dosage Forms and Strengths

Tablet

  • 5 mg
  • 10 mg
  • 20 mg
  • 100 mg

Injectable solution

  • 10 mg/mL

Dosage Considerations – Should be Given as Follows:

Congestive Heart Failure

  • 10-20 mg orally/intravenously once daily initially; doubled until desired diuretic effect is achieved; individual dose not to exceed 200 mg

Chronic Renal Failure

  • 20 mg orally/intravenously once daily initially; doubled until desired diuretic effect is achieved; individual dose not to exceed 200 mg

Hepatic Cirrhosis

Hypertension

  • 2.5-5 mg/day orally initially; increased to 10 mg/day orally in 4-6 weeks as needed

Dosing Considerations

Use for fluid retention refractory to thiazides or with impaired renal function

Overdose management

  • Normal saline may be used for volume replacement
  • Dopamine or norepinephrine may be used to treat hypotension
  • If dysrhythmia due to decreased potassium or magnesium is suspected, replace aggressively
  • Discontinue treatment if no symptoms are apparent after 6 hours

Pediatric: Safety and efficacy not established

Medically Reviewed by a Doctor on 9/6/2017



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