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Triamterene

Medical and Pharmacy Editor:

Brand Name: Dyrenium

Generic Name: Triamterene

Drug Class: Diuretics, Potassium-Sparing

What Is Triamterene and How Does It Work?

Triamterene is a prescription drug indicated in the treatment of edema associated with congestive heart failure, cirrhosis of the liver and the nephrotic syndrome; steroid-induced edema, idiopathic edema and edema due to secondary hyperaldosteronism.

Triamterene may be used alone or with other diuretics, either for its added diuretic effect or its potassium-sparing potential. It also promotes increased diuresis when patients prove resistant or only partially responsive to thiazides or other diuretics because of secondary hyperaldosteronism.

Triamterene is available under the following different brand names: Triamterene.

Dosage of Triamterene:

Capsule

  • 50 mg
  • 100 mg

Dosage Considerations – Should be Given as Follows:

Edema

Adults

  • 100-300 mg/day orally each day or divided every 12 hours

Geriatric

  • 50-300 mg/day orally each day or divided every 12 hours

Hypertension

Adults

  • 100-300 mg/day orally each day or divided every 12 hours

Geriatric:

  • 50-300 mg/day orally each day or divided every 12 hours

Pediatric (off-label)

  • Safety and efficacy not established
  • 1-2 mg/kg/day orally divided every 12 hours
  • Maximum dose: 3-4 mg/kg/day orally divided every 12 hours up to 300 mg/day

Renal Impairment

Adult

  • Creatinine clearance: under 10 mg: do not use

Hepatic Impairment

Adult

  • Reduce dose in patients with cirrhosis
Medically Reviewed by a Doctor on 6/8/2017



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