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How does the heart work?

The heart is a two stage electric pump whose job it is to circulate blood through the body. There is a group of cells that serve as an automatic pacemaker located in the atrium that generates an electrical current that spreads to the heart muscle cells to generate a coordinated squeeze, so that the pump can function.

The heart has four chambers, the right and left atria (singular= atrium) and the right and left ventricles. The right side of the heart pumps blood to the lungs while the left side pumps it to the rest of the body.

Blood from the body is collected in the right atrium and is pushed into the right ventricle with a small beat of the upper chamber of the heart. The right ventricle then pumps the blood to the lungs to pick up oxygen. They oxygen-rich blood returns to the left atrium where the small atrial beat pushes it to the left ventricle. The left ventricle is much thicker than the right because it needs t...

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Cordarone Consumer (continued)

DRUG INTERACTIONS: See also How to Use section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Many drugs besides amiodarone may affect the heart rhythm (QT prolongation), including dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), quinolone antibiotics (such as levofloxacin), among others. (See also Precautions section.)

Other medications can affect the removal of amiodarone from your body, which may affect how amiodarone works. Examples include azole antifungals (such as itraconazole), cimetidine, protease inhibitors (such as indinavir), rifamycins (such as rifampin), St. John's wort, among others.

Amiodarone can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include beta blockers (such as propranolol), calcium channel blockers (such as diltiazem, verapamil), clopidogrel, cyclosporine, digoxin, phenytoin, certain "statin" drugs (atorvastatin, lovastatin, simvastatin), trazodone, warfarin, among others.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: weakness, severe dizziness, very slow heartbeat, fainting.

NOTES: Do not share this medication with others.

Laboratory and/or medical tests (such as EKG, chest X-rays, lung tests, liver tests, thyroid tests, eye exams) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Keep all laboratory and medical appointments.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).

Information last revised May 2010 Copyright(c) 2010 First DataBank, Inc.

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