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Cordarone IV

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Cordarone IV

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Cordarone IV
(amiodarone hydrochloride) Intravenous

This products label may have been revised after this insert was used in production. For further product information and current package insert, please visit www.wyeth.com or call our medical communications department toll-free at 1-800-934-5556.

DRUG DESCRIPTION

Cordarone Intravenous (Cordarone I.V.) contains amiodarone HCl (C25H29I2NO3· HCl), a class III antiarrhythmic drug. Amiodarone HCl is (2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride. Amiodarone HCl has the following structural formula:

Amiodarone HCl is a white to slightly yellow crystalline powder, and is very slightly soluble in water. It has a molecular weight of 681.78 and contains 37.3% iodine by weight. Cordarone I.V. is a sterile clear, pale-yellow micellar solution visually free from particulates. Each milliliter of the Cordarone I.V. formulation contains 50 mg of amiodarone HCl, 20.2 mg of benzyl alcohol, 100 mg of polysorbate 80, and water for injection.

Cordarone I.V. contains polysorbate 80, which is known to leach di-(2-ethylhexyl)phthalate (DEHP) from polyvinylchloride (PVC) (see DOSAGE AND ADMINISTRATION).

Last reviewed on RxList: 7/22/2005
This monograph has been modified to include the generic and brand name in many instances.

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Additional Cordarone IV Information

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