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Lotion, 0.05% Flurandrenolide Lotion, USP
Cordran® (flurandrenolide, USP) is a potent corticosteroid intended for topical use. Flurandrenolide occurs as white to off-white, fluffy, crystalline powder and is odorless. Flurandrenolide is practically insoluble in water and in ether. One g dissolves in 72 mL of alcohol and in 10 mL of chloroform. The molecular weight of flurandrenolide is 436.52.
The chemical name of flurandrenolide is Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis (oxy)]-, (6α, 11β, 16α)-; its empirical formula is C24H33FO6. The structure is as follows:
Each mL of Cordran Lotion contains 0.5 mg (1.145 μmol) (0.05%) flurandrenolide in an oil-in-water emulsion base composed of glycerin, cetyl alcohol, stearic acid, glyceryl monostearate, mineral oil, polyoxyl 40 stearate, menthol, benzyl alcohol, and purified water.
What are the possible side effects of flurandrenolide topical (Cordran, Cordran SP, Cordran Tape)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have signs of absorbing flurandrenolide topical through your skin, such as:
- blurred vision, or seeing halos around lights;
- headache, back ache, weakness, confusion, mood changes;
- sleep problems (insomnia);
- weight gain, puffiness in your face;
- muscle weakness, feeling tired;...
Last reviewed on RxList: 8/5/2011
This monograph has been modified to include the generic and brand name in many instances.
Additional Cordran Lotion Information
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