"The U.S. Food and Drug Administration today approved Orbactiv (oritavancin), a new antibacterial drug to treat adults with skin infections.
Orbactiv is approved to treat patients with acute bacterial skin and skin structure infections (ABSS"...
For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions.
DOSAGE AND ADMINISTRATION
If an infection develops, the use of Cordran Tape (flurandrenolide tape) and other occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Replacement of the tape every 12 hours produces the lowest incidence of adverse reactions, but it may be left in place for 24 hours if it is well tolerated and adheres satisfactorily. When necessary, the tape may be used at night only and removed during the day.
If ends of the tape loosen prematurely, they may be trimmed off and replaced with fresh tape.
The directions given below are included on a separate package insert for the patient to follow unless otherwise instructed by the physician.
APPLICATION OF CORDRAN TAPE (flurandrenolide tape)
IMPORTANT: Skin should be clean and dry before tape is applied. Tape should always be cut, never torn.
DIRECTIONS FOR USE:
- Prepare skin as directed by your physician or as follows: Gently clean the area to be covered to remove scales, crusts, dried exudates, and any previously used ointments or creams. A germicidal soap or cleanser should be used to prevent the development of odor under the tape. Shave or clip the hair in the treatment area to allow good contact with the skin and comfortable removal. If shower or tub bath is to be taken, it should be completed before the tape is applied. The skin should be dry before application of the tape.
- Remove tape from package and cut a piece slightly larger than area to be covered. Round off corners.
- Pull white paper from transparent tape. Be careful that tape does not stick to itself.
- Apply tape, keeping skin smooth; press tape into place.
REPLACEMENT OF TAPE:
Unless instructed otherwise by your physician, replace tape after 12 hours. Cleanse skin and allow it to dry for 1 hour before applying new tape.
IF IRRITATION OR INFECTION DEVELOPS, REMOVE TAPE AND CONSULT PHYSICIAN.
4 mcg/sq cm-small roll, 24 in x 3 in (60 cm x 7.5 cm)
4 mcg/sq cm-large roll, 80 in x 3 in (200 cm x 7.5 cm) NDC 55515-014-80
Directions for the patient are included in each package.
Store at 25°C (77°F); excursions permitted to15-30°C (59-86°F).
Bard JW: Flurandrenolide tape in the treatment of lichen simplex chronicus. J Ky Med Assoc 1969;67:668.
Baxter DL, Stoughton RB: Mitotic index of psoriatic lesions treated with anthralin, glucocorticosteroid and occlusion only. J Invest Dermatol 1970;54:410.
Compilation of clinical reports on Cordran Tape (flurandrenolide tape) received by Eli Lilly and Company.
Halprin KM, Fukui K, Ohkawara A: Flurandrenolone (Cordran) tape and carbohydrate metabolizing enzymes. Arch Dermatol 1969;100:336.
Labow TA, Eisert J, Sanders SL: Flurandrenolide tape in treatment of psoriasis. NY State J Med 1969;69:3138.
Ronchese F: Flurandrenolone tape therapy. RI Med J 1969;52:389.
Sellers FM: Investigative study of flurandrenolone tape in a series of ambulatory outpatients. J Indiana State Med Assoc 1970;63:34.
Weiner MA: Flurandrenolone tape, a new preparation for occlusive therapy, J Invest Dermatol 1966;47:63.
Mfd. by 3M Company, St. Paul, MN 55144. Mfd. For: Oclassen DERMATOLOGICS, A Division of Watson Pharma, Inc. Corona, CA 92880. FDA revision date: 7/19/2000
Last reviewed on RxList: 9/25/2008
This monograph has been modified to include the generic and brand name in many instances.
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