Cormax Ointment (Clobetasol Propionate Ointment) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 27, 2012

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Cormax Ointment

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Cormax® Ointment 0.05%
(clobetasol propionate) Ointment, USP

DRUG DESCRIPTION

Cormax Ointment contains the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Chemically, clobetasol propionate is 21-chloro-9-fluoro-11ß,17-dihydroxy- 16ß-methylpregna-1,4-diene-3,20-dione,17-propionate, and it has the following structural formula:

Cormax®Ointment 0.05% (Clobetasol Propionate) Structural Formula Illustration

Clobetasol propionate has the molecular formula C₂₅H₃₂CIFO₅ and a molecular weight of 467. It is a white to cream-colored crystalline powder insoluble in water.

Each gram of Cormax Ointment contains 0.5 mg clobetasol propionate in a base composed of propylene glycol, sorbitan sesquioleate, and white petrolatum.

What are the precautions when taking clobetasol propionate ointment (Cormax Ointment)?

Before using clobetasol, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, immune system problems, certain skin conditions (rosacea, perioral dermatitis).

Do not use if there is an infection or sore present in the area to be treated.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore,...

Read All Potential Precautions of Cormax Ointment »

Last reviewed on RxList: 7/14/2011
This monograph has been modified to include the generic and brand name in many instances.